Compile Data Set for Download or QSAR
maximum 50k data
Found 89 of ic50 data for complexid = 15,50001094
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM47224(US9073917, 2-inventive)
Affinity DataIC50:  1nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50277545(4-(9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-benzo[...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50175305(CHEMBL3600873)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167515(US9073917, 12- comparative)
Affinity DataIC50:  3nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167510(US9073917, 7- comparative)
Affinity DataIC50:  4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM117012(US8637532, 739)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167506(US9073917, 1-inventive)
Affinity DataIC50:  4nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167507(US9073917, 4- comparative)
Affinity DataIC50:  6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167508(US9073917, 5- comparative)
Affinity DataIC50:  6nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574278(CHEMBL4854144)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50:  8nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167513(US9073917, 10- comparative)
Affinity DataIC50:  9nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM116525(US8637532, 211)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167516(US9073917, 13- comparative)
Affinity DataIC50:  10nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167509(US9073917, 6- comparative)
Affinity DataIC50:  13nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM209861(5-(3-ethylsulfonylphenyl)-3,8-dimethyl-N-(1-methyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of Aurora B/INCENP (unknown origin) pre-incubated for 1 hr followed by FL-PKAtide substrate and ATP additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50244953(CHEMBL4063500)
Affinity DataIC50:  19nMAssay Description:Binding affinity towards [3H]quipazine labeled 5-hydroxytryptamine 3 receptor sites in HG108-15More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167511(US9073917, 8- comparative)
Affinity DataIC50:  21nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574272(CHEMBL4875416)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574268(CHEMBL4851020)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574269(CHEMBL4857965)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574270(CHEMBL4855657)
Affinity DataIC50:  47nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574279(CHEMBL4869229)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574274(CHEMBL4860970)
Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574275(CHEMBL4856439)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM167512(US9073917, 11- comparative | US9073917, 9- compara...)
Affinity DataIC50:  107nMAssay Description:The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198027(CHEMBL3921246)
Affinity DataIC50:  150nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574277(CHEMBL4871106)
Affinity DataIC50:  170nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574271(CHEMBL4876446)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467633(CHEMBL4291945)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574276(CHEMBL4846712)
Affinity DataIC50:  233nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574273(CHEMBL4871853)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198044(CHEMBL3903187)
Affinity DataIC50:  830nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50574280(CHEMBL4853030)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant full length GST-tagged human Aurora B (1 to 344 residues) co-expressed with N-terminal His-tagged human recombinant INCENP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198086(CHEMBL3985313)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198082(CHEMBL3904239)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198081(CHEMBL3915550)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198045(CHEMBL3975102)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198080(CHEMBL3932394)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM60452(US9073917, 3-comparative)
Affinity DataIC50:  3.80E+3nMAssay Description:The effect of the compounds of the invention on the activity of the enzyme PDE3 was evaluated by the company CEREP (Le bois I'Evêque, 86600 Celle...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467663(CHEMBL4285153)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467637(CHEMBL4287010)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50198079(CHEMBL3924918)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467634(CHEMBL4284904)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467650(CHEMBL4282883)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467671(CHEMBL4278479)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467639(CHEMBL4283270)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467642(CHEMBL4280691)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467649(CHEMBL4283403)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM50467670(CHEMBL4285648)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of recombinant human FLAG/His6-tagged Aurora-B (2 to 344 residues)/GST-tagged INCENP preincubated for 30 mins followed by 5FAM-PKA-tide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
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