Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 7145
TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923({6-Methylamino-2-[(pyridin-3-ylmethyl)-amino]-thie...)
Affinity DataIC50: 1.40nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925({6-dimethylamino-2-[(pyridine-3-ylmethyl)-amino]-t...)
Affinity DataIC50: 6.5nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924({6-Ethylamino-2-[(pyridin-3-ylmethyl)-amino]-thien...)
Affinity DataIC50: 6.70nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922({6-Amino-2-[(pyridin-3-ylmethyl)-amino]-thieno[3,2...)
Affinity DataIC50: 7.10nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925({6-dimethylamino-2-[(pyridine-3-ylmethyl)-amino]-t...)
Affinity DataIC50: 19.4nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923({6-Methylamino-2-[(pyridin-3-ylmethyl)-amino]-thie...)
Affinity DataIC50: 22.9nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50: 36.7nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924({6-Ethylamino-2-[(pyridin-3-ylmethyl)-amino]-thien...)
Affinity DataIC50: 37.3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50: 52.3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923({6-Methylamino-2-[(pyridin-3-ylmethyl)-amino]-thie...)
Affinity DataIC50: 57.6nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 68.9nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924({6-Ethylamino-2-[(pyridin-3-ylmethyl)-amino]-thien...)
Affinity DataIC50: 118nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925({6-dimethylamino-2-[(pyridine-3-ylmethyl)-amino]-t...)
Affinity DataIC50: 130nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50: 161nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50: 216nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922({6-Amino-2-[(pyridin-3-ylmethyl)-amino]-thieno[3,2...)
Affinity DataIC50: 233nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 256nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310923({6-Methylamino-2-[(pyridin-3-ylmethyl)-amino]-thie...)
Affinity DataIC50: 277nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 308nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310925({6-dimethylamino-2-[(pyridine-3-ylmethyl)-amino]-t...)
Affinity DataIC50: 318nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50: 361nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310924({6-Ethylamino-2-[(pyridin-3-ylmethyl)-amino]-thien...)
Affinity DataIC50: 726nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A3 [I248L](Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50: 747nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM178000(US9120807, 12)
Affinity DataIC50: 828nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922({6-Amino-2-[(pyridin-3-ylmethyl)-amino]-thieno[3,2...)
Affinity DataIC50: 1.10E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM50310922({6-Amino-2-[(pyridin-3-ylmethyl)-amino]-thieno[3,2...)
Affinity DataIC50: 1.40E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177999(US9120807, 11)
Affinity DataIC50: 3.75E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM177998(US9120807, 10)
Affinity DataIC50: 3.75E+3nMAssay Description:The use of a Fluorometric Imaging Plate Reader (FLIPR) to measure calcium flux in Adenosine-receptor expressing cells is a well-established technique...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
Go to US Patent