Compile Data Set for Download or QSAR
Found 52 Enz. Inhib. hit(s) with all data for entry = 50006157
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
Affinity DataEC50:  45nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045271(4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-1-methyl-...)
Show SMILES C\C(=C/c1ccc2SCCC(C)(C)c2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H22O2S/c1-14(16-5-7-17(8-6-16)20(22)23)12-15-4-9-19-18(13-15)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12+
Affinity DataEC50:  40nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
Affinity DataEC50:  22nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045267(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H26O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h7-12,14H,5-6,13H2,1-4H3,(H,22,23)/b12-7+,15-14+
Affinity DataEC50:  35nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045268(4-[(Z)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-
Affinity DataEC50:  700nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045269(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H26O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h7-12,14H,5-6,13H2,1-4H3,(H,22,23)/b12-7+,15-14-
Affinity DataEC50:  5.00E+3nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045270(4-[1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(=C\c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H28O2/c1-16(18-7-9-19(10-8-18)22(25)26)14-17-6-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045271(4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-1-methyl-...)
Show SMILES C\C(=C/c1ccc2SCCC(C)(C)c2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H22O2S/c1-14(16-5-7-17(8-6-16)20(22)23)12-15-4-9-19-18(13-15)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12+
Affinity DataEC50:  45nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
Affinity DataEC50:  12nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045272(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(CCC1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H28O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h8-11,14H,5-7,12-13H2,1-4H3,(H,22,23)/b15-14+
Affinity DataEC50:  20nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045273(4-[2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]-ben...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2SCCC(C)(C)c2c1
Show InChI InChI=1S/C21H22O2S/c1-14(12-15-4-6-16(7-5-15)20(22)23)17-8-9-19-18(13-17)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12-
Affinity DataEC50:  250nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045272(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(CCC1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H28O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h8-11,14H,5-7,12-13H2,1-4H3,(H,22,23)/b15-14+
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31892(9-cis retinoic acid | 9C-RA | CHEMBL705 | Panretin...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8-,16-14+
Affinity DataEC50:  13nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045274(4-[2-(4,4-Dimethyl-thiochroman-6-yl)-1-methyl-viny...)
Show SMILES C\C(=C\c1ccc2SCCC(C)(C)c2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H22O2S/c1-14(16-5-7-17(8-6-16)20(22)23)12-15-4-9-19-18(13-15)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12-
Affinity DataEC50:  2.80E+3nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045270(4-[1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(=C\c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H28O2/c1-16(18-7-9-19(10-8-18)22(25)26)14-17-6-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-
Affinity DataEC50:  1.10E+3nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045275(2'-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphtha...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccccc1-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C27H28O2/c1-26(2)15-16-27(3,4)24-17-20(13-14-23(24)26)22-8-6-5-7-21(22)18-9-11-19(12-10-18)25(28)29/h5-14,17H,15-16H2,1-4H3,(H,28,29)
Affinity DataEC50:  2.80E+3nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
Affinity DataEC50:  27nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
Affinity DataEC50:  430nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045271(4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-1-methyl-...)
Show SMILES C\C(=C/c1ccc2SCCC(C)(C)c2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H22O2S/c1-14(16-5-7-17(8-6-16)20(22)23)12-15-4-9-19-18(13-15)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12+
Affinity DataEC50:  47nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045274(4-[2-(4,4-Dimethyl-thiochroman-6-yl)-1-methyl-viny...)
Show SMILES C\C(=C\c1ccc2SCCC(C)(C)c2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H22O2S/c1-14(16-5-7-17(8-6-16)20(22)23)12-15-4-9-19-18(13-15)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12-
Affinity DataEC50:  2.10E+3nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
Affinity DataEC50:  24nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045274(4-[2-(4,4-Dimethyl-thiochroman-6-yl)-1-methyl-viny...)
Show SMILES C\C(=C\c1ccc2SCCC(C)(C)c2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H22O2S/c1-14(16-5-7-17(8-6-16)20(22)23)12-15-4-9-19-18(13-15)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12-
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045268(4-[(Z)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-
Affinity DataEC50:  1.00E+3nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045276(4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Show SMILES C\C(=C/c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H28O2/c1-16(18-7-9-19(10-8-18)22(25)26)14-17-6-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
Affinity DataEC50:  25nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045275(2'-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphtha...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccccc1-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C27H28O2/c1-26(2)15-16-27(3,4)24-17-20(13-14-23(24)26)22-8-6-5-7-21(22)18-9-11-19(12-10-18)25(28)29/h5-14,17H,15-16H2,1-4H3,(H,28,29)
Affinity DataEC50:  100nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
Affinity DataEC50:  12nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045268(4-[(Z)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-
Affinity DataEC50:  2.70E+3nMAssay Description:Effective concentration against RXR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045269(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H26O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h7-12,14H,5-6,13H2,1-4H3,(H,22,23)/b12-7+,15-14-
Affinity DataEC50:  2.00E+3nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM31883(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
Affinity DataEC50:  8nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045276(4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Show SMILES C\C(=C/c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H28O2/c1-16(18-7-9-19(10-8-18)22(25)26)14-17-6-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
Affinity DataEC50:  19nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045277(4-[2-(1,2,3,4-Tetrahydro-1,4-methano-naphthalen-6-...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2C3CCC(C3)c2c1
Show InChI InChI=1S/C21H20O2/c1-13(10-14-2-4-15(5-3-14)21(22)23)16-8-9-19-17-6-7-18(11-17)20(19)12-16/h2-5,8-10,12,17-18H,6-7,11H2,1H3,(H,22,23)/b13-10-
Affinity DataEC50:  70nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045274(4-[2-(4,4-Dimethyl-thiochroman-6-yl)-1-methyl-viny...)
Show SMILES C\C(=C\c1ccc2SCCC(C)(C)c2c1)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H22O2S/c1-14(16-5-7-17(8-6-16)20(22)23)12-15-4-9-19-18(13-15)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12-
Affinity DataEC50:  1.50E+3nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045272(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(CCC1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H28O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h8-11,14H,5-7,12-13H2,1-4H3,(H,22,23)/b15-14+
Affinity DataEC50:  210nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
Affinity DataEC50:  6nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045268(4-[(Z)-2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-
Affinity DataEC50:  2.20E+3nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045273(4-[2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]-ben...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2SCCC(C)(C)c2c1
Show InChI InChI=1S/C21H22O2S/c1-14(12-15-4-6-16(7-5-15)20(22)23)17-8-9-19-18(13-17)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12-
Affinity DataEC50:  2.30E+3nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045266(4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2SCCC(C)(C)c2c1
Show InChI InChI=1S/C21H22O2S/c1-14(12-15-4-6-16(7-5-15)20(22)23)17-8-9-19-18(13-17)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12+
Affinity DataEC50:  30nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045273(4-[2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]-ben...)
Show SMILES C\C(=C\c1ccc(cc1)C(O)=O)c1ccc2SCCC(C)(C)c2c1
Show InChI InChI=1S/C21H22O2S/c1-14(12-15-4-6-16(7-5-15)20(22)23)17-8-9-19-18(13-17)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12-
Affinity DataEC50:  1.10E+3nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045278(4-[(E)-2-(1,2,3,4-Tetrahydro-1,4-methano-naphthale...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2C3CCC(C3)c2c1
Show InChI InChI=1S/C21H20O2/c1-13(10-14-2-4-15(5-3-14)21(22)23)16-8-9-19-17-6-7-18(11-17)20(19)12-16/h2-5,8-10,12,17-18H,6-7,11H2,1H3,(H,22,23)/b13-10+
Affinity DataEC50:  550nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045267(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H26O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h7-12,14H,5-6,13H2,1-4H3,(H,22,23)/b12-7+,15-14+
Affinity DataEC50:  240nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045276(4-[(E)-1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tet...)
Show SMILES C\C(=C/c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H28O2/c1-16(18-7-9-19(10-8-18)22(25)26)14-17-6-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
Affinity DataEC50:  37nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045272(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(CCC1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H28O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h8-11,14H,5-7,12-13H2,1-4H3,(H,22,23)/b15-14+
Affinity DataEC50:  550nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor gamma(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045279(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(CCC1=C(C)CCCC1(C)C)=C\c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H28O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h8-11,14H,5-7,12-13H2,1-4H3,(H,22,23)/b15-14-
Affinity DataEC50:  1.30E+3nMAssay Description:Effective concentration against RAR-gamma receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045267(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H26O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h7-12,14H,5-6,13H2,1-4H3,(H,22,23)/b12-7+,15-14+
Affinity DataEC50:  5nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045275(2'-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphtha...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccccc1-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C27H28O2/c1-26(2)15-16-27(3,4)24-17-20(13-14-23(24)26)22-8-6-5-7-21(22)18-9-11-19(12-10-18)25(28)29/h5-14,17H,15-16H2,1-4H3,(H,28,29)
Affinity DataEC50:  3.20E+3nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045270(4-[1-Methyl-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(=C\c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C24H28O2/c1-16(18-7-9-19(10-8-18)22(25)26)14-17-6-11-20-21(15-17)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14-
Affinity DataEC50:  1.90E+3nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045266(4-[(E)-2-(4,4-Dimethyl-thiochroman-6-yl)-propenyl]...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2SCCC(C)(C)c2c1
Show InChI InChI=1S/C21H22O2S/c1-14(12-15-4-6-16(7-5-15)20(22)23)17-8-9-19-18(13-17)21(2,3)10-11-24-19/h4-9,12-13H,10-11H2,1-3H3,(H,22,23)/b14-12+
Affinity DataEC50:  15nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
TargetRetinoic acid receptor alpha(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50032219((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
Show InChI InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+
Affinity DataEC50:  85nMAssay Description:Effective concentration against RAR-alpha receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045278(4-[(E)-2-(1,2,3,4-Tetrahydro-1,4-methano-naphthale...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2C3CCC(C3)c2c1
Show InChI InChI=1S/C21H20O2/c1-13(10-14-2-4-15(5-3-14)21(22)23)16-8-9-19-17-6-7-18(11-17)20(19)12-16/h2-5,8-10,12,17-18H,6-7,11H2,1H3,(H,22,23)/b13-10+
Affinity DataEC50:  1.10E+3nMAssay Description:Effective concentration against RAR-beta receptorMore data for this Ligand-Target Pair
TargetRetinoic acid receptor beta(Homo sapiens (Human))
SRI International

Curated by ChEMBL
LigandPNGBDBM50045269(4-[2-Methyl-4-(2,6,6-trimethyl-cyclohex-1-enyl)-bu...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C21H26O2/c1-15(14-17-8-10-18(11-9-17)20(22)23)7-12-19-16(2)6-5-13-21(19,3)4/h7-12,14H,5-6,13H2,1-4H3,(H,22,23)/b12-7+,15-14-
Affinity DataEC50:  1.80E+3nMAssay Description:Effective concentration against Retinoic acid receptor betaMore data for this Ligand-Target Pair
Displayed 1 to 50 (of 52 total ) | Next | Last >>
Jump to: