Compile Data Set for Download or QSAR
Report error Found 59 Enz. Inhib. hit(s) with all data for entry = 50044637
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50176808(6-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-be...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50322358(4'-Chloro-biphenyl-4-carboxylic acid((R)-2-imidazo...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023361(Cta018 | Lunacalcipol)
Affinity DataIC50: 27nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023359(CHEMBL3329778)
Affinity DataIC50: 36nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023348(CHEMBL3329769)
Affinity DataIC50: 110nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023349(CHEMBL3329770)
Affinity DataIC50: 140nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023348(CHEMBL3329769)
Affinity DataIC50: 160nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023355(CHEMBL3329774)
Affinity DataIC50: 160nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023359(CHEMBL3329778)
Affinity DataIC50: 180nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023355(CHEMBL3329774)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023360(CHEMBL3329779)
Affinity DataIC50: 230nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023347(CHEMBL3329768)
Affinity DataIC50: 240nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023346(CHEMBL3329767)
Affinity DataIC50: 260nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023350(CHEMBL3329771)
Affinity DataIC50: 280nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023349(CHEMBL3329770)
Affinity DataIC50: 330nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023347(CHEMBL3329768)
Affinity DataIC50: 340nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 360nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50322357((E)-4-N-(2-(1H-imidazol-1-yl)-2-phenylethyl)-4-sty...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 470nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50322357((E)-4-N-(2-(1H-imidazol-1-yl)-2-phenylethyl)-4-sty...)
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023350(CHEMBL3329771)
Affinity DataIC50: 510nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023360(CHEMBL3329779)
Affinity DataIC50: 600nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023346(CHEMBL3329767)
Affinity DataIC50: 600nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023351(CHEMBL3329772)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023352(CHEMBL3329773)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023358(CHEMBL3329777)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023357(CHEMBL3329776)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023356(CHEMBL3329775)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023359(CHEMBL3329778)
Affinity DataKi:  5.70nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023348(CHEMBL3329769)
Affinity DataKi:  7.80nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023349(CHEMBL3329770)
Affinity DataKi:  9.70nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023355(CHEMBL3329774)
Affinity DataKi:  11nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023359(CHEMBL3329778)
Affinity DataKi:  13nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023346(CHEMBL3329767)
Affinity DataKi:  19nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023363(CHEMBL3360784)
Affinity DataKi:  21nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023347(CHEMBL3329768)
Affinity DataKi:  24nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023348(CHEMBL3329769)
Affinity DataKi:  26nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50322357((E)-4-N-(2-(1H-imidazol-1-yl)-2-phenylethyl)-4-sty...)
Affinity DataKi:  28nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023355(CHEMBL3329774)
Affinity DataKi:  33nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataKi:  33nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023350(CHEMBL3329771)
Affinity DataKi:  36nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023360(CHEMBL3329779)
Affinity DataKi:  37nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023362(CHEMBL3360783)
Affinity DataKi:  39nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023347(CHEMBL3329768)
Affinity DataKi:  40nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023364(CHEMBL3360785)
Affinity DataKi:  42nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023360(CHEMBL3329779)
Affinity DataKi:  42nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023350(CHEMBL3329771)
Affinity DataKi:  45nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50023349(CHEMBL3329770)
Affinity DataKi:  53nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
Target25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial(Mouse)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataKi:  58nMAssay Description:Inhibition of mouse CYP27B1 using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reductase and NADPH incubated at 37 degC for 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
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