Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50022084
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231520(CHEMBL252937 | US8476306, 6.12 | (R)-N-[(S)-1-(4-c...)
Affinity DataIC50: 20nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50147422(3-(4-Chloro-1-guanidino-isoquinolin-7-yl)-benzoic ...)
Affinity DataIC50: 37nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231528(4-(2-aminoethoxy)-N-(3-chloro-2-ethoxy-5-(piperidi...)
Affinity DataIC50: 72nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM23891(ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-...)
Affinity DataIC50: 410nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231527((R)-N-[(3-chloro-2-ethoxy 5-(1-piperidinyl)phenyl]...)
Affinity DataIC50: 460nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231526(N-[(3-chloro-5-(1-piperidinyl)phenyl] 4-[(2-amino)...)
Affinity DataIC50: 520nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231523(N-[(3,5-di-isopropoxy)phenyl] 4-[(2-amino)ethoxy]-...)
Affinity DataIC50: 720nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231529(4-(2-aminoethoxy)-N-(2,5-diethoxyphenyl)-3,5-dimet...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231524(N-[(3-fluoro-5-(4-morpholinyl)phenyl] 4-[(2-amino)...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231525(N-[3-(isopropyloxy)phenyl] 4-[(2-amino)ethoxy]-3,5...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231519(N-[3-(isopropyloxy)phenyl] 4-[(2-amino)ethoxy]-3,5...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231522(N-(2-methoxyphenyl) 4-[(2-amino)ethoxy]-3,5-dichlo...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231518(N-phenyl 4-[(2-amino)ethoxy]-3,5-dichlorobenzamide...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50231521(4-(2-aminoethoxy)-3,5-dichlorobenzoic acid | 4-[(2...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50135883((R)-1-(2,6-dimethylphenoxy)propan-2-amine | (2R)-1...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed