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Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50027409
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246361(CHEMBL455195 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246466((3R,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5931(BMS-387072 | CHEMBL296468 | N-(5-{[(5-tert-butyl-1...)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDK9/Cyclin T (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246465((3R,5R)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246415(CHEMBL454645 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  14nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246360(CHEMBL455194 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  15nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246413(CHEMBL509012 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  17nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5929((+/-)-N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]met...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246466((3R,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246464((3S,5R)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  36nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5931(BMS-387072 | CHEMBL296468 | N-(5-{[(5-tert-butyl-1...)
Affinity DataIC50:  46nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 7(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5931(BMS-387072 | CHEMBL296468 | N-(5-{[(5-tert-butyl-1...)
Affinity DataIC50:  62nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246414(CHEMBL508506 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  95nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 7(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246466((3R,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CDK7/Cyclin H (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246466((3R,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246466((3R,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246416(CHEMBL454646 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  140nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246467((3S,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of CDK2/Cyclin A (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246416(CHEMBL454646 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  270nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246415(CHEMBL454645 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  370nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5931(BMS-387072 | CHEMBL296468 | N-(5-{[(5-tert-butyl-1...)
Affinity DataIC50:  480nMAssay Description:Inhibition of CDK1/Cyclin B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5931(BMS-387072 | CHEMBL296468 | N-(5-{[(5-tert-butyl-1...)
Affinity DataIC50:  550nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM5929((+/-)-N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]met...)
Affinity DataIC50:  550nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246361(CHEMBL455195 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  680nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246465((3R,5R)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  770nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246413(CHEMBL509012 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  810nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246360(CHEMBL455194 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246414(CHEMBL508506 | N-(5-((5-tert-butyloxazol-2-yl)meth...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246464((3S,5R)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50246467((3S,5S)-N-(5-((5-tert-butyloxazol-2-yl)methylthio)...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of CDK9-mediated RNA pol 2 phosphorylation at ser2 in human HCT116 cells after 16 hrs by HCS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed