Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50038742
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50195927(N-(5-methyl-2,4,6-trioxo-hexahydropyrimidin-5-yl)-...)
Affinity DataIC50: 0.0260nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247788((2R,3S)-N1-((S)-3-(4-guanidinophenyl)-1-(methylami...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50229322((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247606(BMS-561392 | (R)-2-((R)-3-amino-3-(4-((2-methylqui...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247896((2S,3R)-4-acetyl-N-(allyloxy)-3-methyl-1-(4-(4-met...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50167485(5-methyl-5-(4-((2-methylquinolin-4-yl)methoxy)phen...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50152901(N-hydroxy-1-methyl-2-((4-((2-methylquinolin-4-yl)m...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247718(N-(3-(hydroxyamino)-3-oxopropyl)-4-((2-methylquino...)
Affinity DataIC50: 1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50183725(N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-(methylsulfon...)
Affinity DataIC50: 1nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM26526(BMCL181958 Compound 1 | CHEMBL148169 | (2R)-N-hydr...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247605((R)-N-hydroxy-2-(3-methyl-1-(4-((2-methylquinolin-...)
Affinity DataIC50: 1nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM23500(CHEMBL209970 | 4-({[4-(but-2-yn-1-yloxy)benzene]su...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50183739(N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)be...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50120689((R)-2-((S)-3-(4-(3,5-bis(trifluoromethyl)benzyloxy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50146476(N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemeth...)
Affinity DataIC50: 2nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247804(Ro-32-7315 | (2S,3R)-2-cinnamyl-N-hydroxy-3-(2-iso...)
Affinity DataIC50: 3nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247896((2S,3R)-4-acetyl-N-(allyloxy)-3-methyl-1-(4-(4-met...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM23498((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50177315(2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-d...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50120696((R)-2-((S)-3-(4-(benzyloxy)phenyl)-3-methyl-2-oxop...)
Affinity DataIC50: 4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50156712(2-(4-(but-2-ynyloxy)phenylsulfinyl)-N-hydroxyoctan...)
Affinity DataIC50: 4nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247806((2R,5R,6S)-6-(N-hydroxyformamido)-N-(3H-1,3-thiazo...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of TACE by cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM23498((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247704(3-(5-(hexa-2,4-dienylidene)-2-oxo-5,6-dihydro-2H-p...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247788((2R,3S)-N1-((S)-3-(4-guanidinophenyl)-1-(methylami...)
Affinity DataIC50: 6nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50126601(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 6nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50136259((2S,3S)-N3-hydroxy-1-methyl-N2-(4-((2-methylquinol...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM23498((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247607((1S,2S)-N1-hydroxy-N2-(4-((2-methylquinolin-4-ylox...)
Affinity DataIC50: 8nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM23498((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50126613(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50111695(5-bromo-N-hydroxy-2-(4-methoxy-N-methylphenylsulfo...)
Affinity DataIC50: 11nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50150246(1-acetyl-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hyd...)
Affinity DataIC50: 12nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50126615(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 17nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50150246(1-acetyl-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hyd...)
Affinity DataIC50: 20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50082556(AG-3340 | 2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benz...)
Affinity DataIC50: 22nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247704(3-(5-(hexa-2,4-dienylidene)-2-oxo-5,6-dihydro-2H-p...)
Affinity DataIC50: 23nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247821(6-bromo-2-(4-(but-2-ynyloxy)-N-methylphenylsulfona...)
Affinity DataIC50: 25nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247704(3-(5-(hexa-2,4-dienylidene)-2-oxo-5,6-dihydro-2H-p...)
Affinity DataIC50: 28nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50111695(5-bromo-N-hydroxy-2-(4-methoxy-N-methylphenylsulfo...)
Affinity DataIC50: 32nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50247805((2R,3S)-3-(N-hydroxyformamido)-2-isobutyl-4-methyl...)
Affinity DataIC50: 40nMAssay Description:Inhibition of TACE by cell free assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50183784(N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of TACE in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50129021(ethyl N-{(1s)-1-[(hydroxyamino)carbonyl]-3-methylb...)
Affinity DataIC50: 76nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Pig)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50167486(5-(4-methylpiperazin-1-yl)-5-(4-((2-methylquinolin...)
Affinity DataIC50: 91nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50111695(5-bromo-N-hydroxy-2-(4-methoxy-N-methylphenylsulfo...)
Affinity DataIC50: 114nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50240611((2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxo...)
Affinity DataIC50: 141nMAssay Description:Inhibition of TACE in human PBMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
The M. S. University of Baroda

Curated by ChEMBL
LigandPNGBDBM50126613(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 147nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
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