Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 2139
LigandPNGBDBM17294(Compound 11 | (13S,14S,15S)-15-methyl-13-nonyltetr...)
Affinity DatapH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
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LigandPNGBDBM17290(EM1745 | E2-adenosine hybrid compound, 8 | [5-(6-a...)
Affinity DataIC50: 52nMpH: 7.4 T: 2°CAssay Description:The enzymatic reaction was performed in the reaction buffer containing substrate, [14C]-estrone, and the test inhibitors. After the reaction, radiola...More data for this Ligand-Target Pair
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LigandPNGBDBM17288([5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-y...)
Affinity DataIC50: 93nMpH: 7.4 T: 2°CAssay Description:The enzymatic reaction was performed in the reaction buffer containing substrate, [14C]-estrone, and the test inhibitors. After the reaction, radiola...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17291([5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-y...)
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:The enzymatic reaction was performed in the reaction buffer containing substrate, [14C]-estrone, and the test inhibitors. After the reaction, radiola...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17290(EM1745 | E2-adenosine hybrid compound, 8 | [5-(6-a...)
Affinity DataKi:  3nM ΔG°:  -50.6kJ/molepH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM17293([5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-y...)
Affinity DataKi:  2.50E+5nM ΔG°:  -21.4kJ/molepH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed