Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 313
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM348(1-Valine Methylamide deriv. 1 | Diol-Based HIV-1 p...)
Affinity DataKi:  0.800nM ΔG°:  -52.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM353((2R,3R,4R,5R)-2,5-bis[(2,4-difluorophenyl)methoxy]...)
Affinity DataKi:  1.12nM ΔG°:  -51.9kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM358(symmetric/asymmetric inhibitor 2 | (2R,3R,4R,5R)-2...)
Affinity DataKi:  1.22nM ΔG°:  -51.7kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM352(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.28nM ΔG°:  -51.6kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM365(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  1.64nM ΔG°:  -51.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM363(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  1.65nM ΔG°:  -51.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM355((2R,3R,4R,5R)-2,5-bis[(2,6-difluorophenyl)methoxy]...)
Affinity DataKi:  1.73nM ΔG°:  -50.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM351(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.79nM ΔG°:  -50.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM350(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.83nM ΔG°:  -50.7kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM349((2R,3R,4R,5R)-2,5-bis[(2-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  1.92nM ΔG°:  -50.6kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM357((2R,3R,4R,5R)-2,5-bis[(3,5-difluorophenyl)methoxy]...)
Affinity DataKi:  1.98nM ΔG°:  -50.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM356(N1,N6-Bis-[(1S)-2-methyl-1-(methylcarbamoyl)propyl...)
Affinity DataKi:  1.98nM ΔG°:  -50.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM354((2R,3R,4R,5R)-2,5-bis[(2,5-difluorophenyl)methoxy]...)
Affinity DataKi:  1.98nM ΔG°:  -50.5kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM359((2R,3R,4R,5R)-2,5-bis[(2-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  3.26nM ΔG°:  -49.3kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM364((2R,3R,4R,5R)-2,5-bis[(2,5-difluorophenyl)methoxy]...)
Affinity DataKi:  3.29nM ΔG°:  -49.2kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM366(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  3.90nM ΔG°:  -48.8kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM362(N1,N6-Bis-[(2R)-hydroxy-1(S)-indanyl]-(2R,3R,4R,5R...)
Affinity DataKi:  4nM ΔG°:  -48.7kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM367((2R,3R,4R,5R)-2,5-bis[(3,5-difluorophenyl)methoxy]...)
Affinity DataKi:  5nM ΔG°:  -48.2kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM361((2R,3R,4R,5R)-2,5-bis[(4-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  5.39nM ΔG°:  -48.0kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Linkoping University

LigandPNGBDBM360((2R,3R,4R,5R)-2,5-bis[(3-fluorophenyl)methoxy]-3,4...)
Affinity DataKi:  7.13nM ΔG°:  -47.3kJ/molepH: 5.0 T: 2°CAssay Description:A fluorimetric assay was used to determine the effects of the inhibitors on HIV-1 protease. This assay used an internally quenched fluorescent peptid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed