Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50000062
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: 79nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239868(CHEMBL4097764)
Affinity DataIC50: 180nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239866(CHEMBL4065018)
Affinity DataIC50: 790nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 helicase activity expressed in baculovirus infected Sf9 cells assessed as redu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239867(CHEMBL4070179)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239865(CHEMBL4060106)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239871(CHEMBL4066070)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239861(CHEMBL4092701)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239861(CHEMBL4092701)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239872(CHEMBL4095148)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239861(CHEMBL4092701)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239861(CHEMBL4092701)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of full length recombinant human N-terminal FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239870(CHEMBL4061514)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239866(CHEMBL4065018)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239868(CHEMBL4097764)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239868(CHEMBL4097764)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-dependent RNA helicase DHX29(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239866(CHEMBL4065018)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239866(CHEMBL4065018)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239864(CHEMBL4074763)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-III(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239863(CHEMBL4087449)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of eIF4G-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A1 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239862(CHEMBL4102900)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed