Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50000080
Affinity DataEC50: 1.71E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 420nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 9.50E+3nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 1.27E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
Affinity DataEC50: 2.81E+4nMAssay Description:Antagonist activity at full length human androgen receptor expressed in mammalian expression system measured after 22 to 24 hrs by luciferase reporte...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: 109nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: 216nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: 417nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: 491nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human ERG expressed in CHOK1 cells by Qpatch clamp methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
3D Structure (crystal)TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [125I]-IPAG from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 38nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: 46nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Drexel University College of Medicine
Curated by ChEMBL
Drexel University College of Medicine
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]-IPAG from sigma1 in human MDA-MB-468 cell membranesMore data for this Ligand-Target Pair
