Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50001634
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK L1196M mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 0.820nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK R1275Q mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK F1174L mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal GST/His6-fused ALK C1156Y mutant expressed in Sf9 insect cells using Tyr 1 peptide as substrate after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R/T790M mutant expressed in Baculovirus expression system using Tyr 4 peptide as substrate after ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M mutant expressed in Baculovirus expression system using Tyr 4 peptide as substrate after 1 hr i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human wild-type GST-tagged ALK expressed in Baculovirus expression system using Tyr 1 peptide as substrate after 1 hr by Z-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human GST-tagged EGFR L858R mutant expressed in Baculovirus expression system using Tyr 4 peptide as substrate after 1 hr i...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50288848(CHEMBL4159909)
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant human wild-type His-tagged EGFR expressed in mammalian expression system using Tyr 4 peptide as substrate after 1 hr in pre...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed