Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with all data for entry = 50003499
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471841(CHEMBL334988)
Affinity DataEC50:  7.50E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223132(CHEMBL30619)
Affinity DataEC50:  3.50E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471846(CHEMBL434822)
Affinity DataEC50:  2.10E+4nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223121(CHEMBL281244)
Affinity DataEC50:  1.05E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223118(CHEMBL31530)
Affinity DataEC50:  600nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223123(CHEMBL31877)
Affinity DataEC50:  1.80E+4nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223055(CHEMBL31439)
Affinity DataEC50:  2.10E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223097(CHEMBL28562)
Affinity DataEC50:  1.70E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223052(CHEMBL30733)
Affinity DataEC50:  700nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223129(CHEMBL30379)
Affinity DataEC50:  1.80E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223187(CHEMBL30966)
Affinity DataEC50:  3.40E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223189(CHEMBL288545)
Affinity DataEC50:  1.80E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223120(CHEMBL31063)
Affinity DataEC50:  200nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223128(CHEMBL31795)
Affinity DataEC50:  2.00E+3nMAssay Description:Increased cAMP accumulation in isoprenaline-induced guinea pig eosinophilsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471096(CHEMBL414613 | RS-14491)
Affinity DataIC50: 4.80nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 6nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223120(CHEMBL31063)
Affinity DataIC50: 30nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471096(CHEMBL414613 | RS-14491)
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223099(CHEMBL288547)
Affinity DataIC50: 80nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223054(CHEMBL434590)
Affinity DataIC50: 200nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223052(CHEMBL30733)
Affinity DataIC50: 200nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223118(CHEMBL31530)
Affinity DataIC50: 200nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223129(CHEMBL30379)
Affinity DataIC50: 230nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 320nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223118(CHEMBL31530)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471840(CHEMBL132107)
Affinity DataIC50: 400nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223052(CHEMBL30733)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223053(CHEMBL30406)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223120(CHEMBL31063)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223125(CHEMBL30407)
Affinity DataIC50: 600nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223132(CHEMBL30619)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223054(CHEMBL434590)
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM15296(Milrinone | CHEMBL189 | 6-methyl-2-oxo-5-pyridin-4...)
Affinity DataIC50: 730nMAssay Description:Inhibitory activity against cGMP inhibited Phosphodiesterase 3, isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223189(CHEMBL288545)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223121(CHEMBL281244)
Affinity DataIC50: 840nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223129(CHEMBL30379)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471843(CHEMBL130514)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223125(CHEMBL30407)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223055(CHEMBL31439)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471850(CHEMBL131059)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223099(CHEMBL288547)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471839(CHEMBL128461)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223055(CHEMBL31439)
Affinity DataIC50: 1.10E+3nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223187(CHEMBL30966)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471839(CHEMBL128461)
Affinity DataIC50: 1.20E+3nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471841(CHEMBL334988)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223128(CHEMBL31795)
Affinity DataIC50: 1.30E+3nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223132(CHEMBL30619)
Affinity DataIC50: 1.40E+3nMAssay Description:Affinity for the high affinity rolipram binding site of phosphodiesterase (PDE IV) by [3H]rolipram displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50223097(CHEMBL28562)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50471840(CHEMBL132107)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory activity against phosphodiesterase 4 isolated from guinea pig ventricular tissueMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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