Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50005543
TargetHistone deacetylase 4(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187543(US9670193, 21 (R)-N-(1-(benzyl(methyl)amino)propan...)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human HDAC-4 (2 to 1084) expressed in baculovirus infected Sf9 cells using acetyl-Gly-Ala-Lys(E-trifluoroacetyl)-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187565(US9670193, 23 (R)-N-(1-(diethylamino)propan-2-yl)-...)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant human HDAC-4 (2 to 1084) expressed in baculovirus infected Sf9 cells using acetyl-Gly-Ala-Lys(E-trifluoroacetyl)-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 4(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187220(US9670193, 10 N-(pyridin-3-ylmethyl)-5-(5-(trifluo...)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human HDAC-4 (2 to 1084) expressed in baculovirus infected Sf9 cells using acetyl-Gly-Ala-Lys(E-trifluoroacetyl)-AMC as sub...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187220(US9670193, 10 N-(pyridin-3-ylmethyl)-5-(5-(trifluo...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant full length human HDAC-6 expressed in baculovirus expression system using acetyl-Gly-Ala-Lys(acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187220(US9670193, 10 N-(pyridin-3-ylmethyl)-5-(5-(trifluo...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant full length human HDAC-1 expressed in baculovirus expression system using acetyl-Gly-Ala-Lys(acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187543(US9670193, 21 (R)-N-(1-(benzyl(methyl)amino)propan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC-6 expressed in baculovirus expression system using acetyl-Gly-Ala-Lys(acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187565(US9670193, 23 (R)-N-(1-(diethylamino)propan-2-yl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC-1 expressed in baculovirus expression system using acetyl-Gly-Ala-Lys(acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187543(US9670193, 21 (R)-N-(1-(benzyl(methyl)amino)propan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC-1 expressed in baculovirus expression system using acetyl-Gly-Ala-Lys(acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM187565(US9670193, 23 (R)-N-(1-(diethylamino)propan-2-yl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC-6 expressed in baculovirus expression system using acetyl-Gly-Ala-Lys(acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed