Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50006681
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502427BDBM50502427(CHEMBL4542517)
Affinity DataIC50: 12nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502413BDBM50502413(CHEMBL4521324)
Affinity DataIC50: 67nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502429BDBM50502429(CHEMBL4475972)
Affinity DataIC50: 140nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502416BDBM50502416(CHEMBL4472455)
Affinity DataIC50: 170nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502436BDBM50502436(CHEMBL4450314)
Affinity DataIC50: 250nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502433BDBM50502433(CHEMBL4575866)
Affinity DataIC50: 250nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502414BDBM50502414(CHEMBL4440399)
Affinity DataIC50: 260nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502434BDBM50502434(CHEMBL4551647)
Affinity DataIC50: 300nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502426BDBM50502426(CHEMBL4448008)
Affinity DataIC50: 360nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502415BDBM50502415(CHEMBL4579512)
Affinity DataIC50: 370nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502438BDBM50502438(CHEMBL4530816)
Affinity DataIC50: 370nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502428BDBM50502428(CHEMBL4584168)
Affinity DataIC50: 380nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502427BDBM50502427(CHEMBL4542517)
Affinity DataKi:  440nMAssay Description:Irreversible inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502418BDBM50502418(CHEMBL4532072)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502419BDBM50502419(CHEMBL4462956)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502435BDBM50502435(CHEMBL4541197)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502437BDBM50502437(CHEMBL4459513)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502433BDBM50502433(CHEMBL4575866)
Affinity DataKi:  3.06E+3nMAssay Description:Irreversible inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502417BDBM50502417(CHEMBL4445957)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502434BDBM50502434(CHEMBL4551647)
Affinity DataKi:  3.90E+3nMAssay Description:Irreversible inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 5 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502425BDBM50502425(CHEMBL1511440)
Affinity DataIC50: 4.78E+3nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502432BDBM50502432(CHEMBL4450161)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502420BDBM50502420(CHEMBL4467704)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502421BDBM50502421(CHEMBL4466228)
Affinity DataIC50: 3.05E+4nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502430BDBM50502430(CHEMBL4460269)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502424BDBM50502424(CHEMBL4593854)
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502431BDBM50502431(CHEMBL4453340)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502412BDBM50502412(CHEMBL4533652)
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502423BDBM50502423(CHEMBL4518844)
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Experimental Drug Development Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50502422BDBM50502422(CHEMBL4438454)
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibition of SMYD3 (unknown origin) using MAP3K2 peptide as substrate pretreated for 30 mins followed by substrate addition and measured after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed