Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50007094
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058182((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataEC50:  300nMAssay Description:concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum. Act...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058172((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataEC50: >1.00E+3nMAssay Description:concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058187((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataEC50:  200nMAssay Description:concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum. Act...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058190((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataEC50: >1.00E+3nMAssay Description:concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058171((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataEC50:  100nMAssay Description:concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058179((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataEC50:  60nMAssay Description:concentration which gave a 50% increase in the response to electrical stimulation against 5-hydroxytryptamine 4 receptor in the guinea pig ileum. Act...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058172((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataIC50: 180nMAssay Description:The antagonist activity was calculated as the concentration which produced a 50% reduction against 5-hydroxytryptamine 4 receptor in guinea pig ileum...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058179((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataIC50: 200nMAssay Description:The antagonist activity was calculated as the concentration which produced a 50% reduction against 5-hydroxytryptamine 4 receptor in guinea pig ileum...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058171((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataIC50: 207nMAssay Description:The antagonist activity was calculated as the concentration which produced a 50% reduction against 5-hydroxytryptamine 4 receptor in guinea pig ileum...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058182((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataIC50: 1.00E+3nMAssay Description:The antagonist activity was calculated as the concentration which produced a 50% reduction against 5-hydroxytryptamine 4 receptor in guinea pig ileum...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM29525(GR 113808 | [3H] GR 113808 | CHEMBL518682 | 3H-GR1...)
Affinity DataKi:  0.150nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058173(CHEMBL50660 | ML10375 | 4-Amino-5-chloro-2-methoxy...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058170((2-Ethoxy-phenyl)-carbamic acid 2-((3R,5S)-3,5-dim...)
Affinity DataKi:  1.05nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM29526(CHEMBL286136 | 2-Piperidinoethyl 4-amino-5-chloro-...)
Affinity DataKi:  1.07nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50454556(CHEMBL2115017)
Affinity DataKi:  1.20nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058172((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  2.40nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058175((2-Ethoxy-phenyl)-carbamic acid 2-piperidin-1-yl-e...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058181((2-Methoxy-phenyl)-carbamic acid 2-((3R,5S)-3,5-di...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058174((5-Chloro-2-methoxy-phenyl)-carbamic acid 2-piperi...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50056401(SDZ-205557 | SDZ 205557 | 2-diethylaminoethyl [2-m...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058185((2-Methoxy-phenyl)-carbamic acid 2-piperidin-1-yl-...)
Affinity DataKi:  8.90nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058180((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  10.2nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058171((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  14.5nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058179((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  25.1nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058168(Phenyl-carbamic acid 2-piperidin-1-yl-ethyl ester ...)
Affinity DataKi:  31.7nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058190((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  39nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058178((3-Chloro-phenyl)-carbamic acid 2-piperidin-1-yl-e...)
Affinity DataKi:  60.8nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058189((2-Methoxy-phenyl)-carbamic acid 3-piperidin-1-yl-...)
Affinity DataKi:  81nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058187((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  125nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058182((4-Amino-5-chloro-2-methoxy-phenyl)-carbamic acid ...)
Affinity DataKi:  150nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058177((3-Methoxy-phenyl)-carbamic acid 2-piperidin-1-yl-...)
Affinity DataKi:  469nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058192((4-Chloro-phenyl)-carbamic acid 2-piperidin-1-yl-e...)
Affinity DataKi:  728nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058184(N-(2-Methoxy-phenyl)-4-piperidin-1-yl-butyramide |...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058183(N-(4-Amino-5-chloro-2-methoxy-phenyl)-4-piperidin-...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058186((4-Methoxy-phenyl)-carbamic acid 2-piperidin-1-yl-...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058188((2-Chloro-phenyl)-carbamic acid 2-piperidin-1-yl-e...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatal membranes by [3H]GR-113808 displacement.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058176((2-Amino-phenyl)-carbamic acid 2-piperidin-1-yl-et...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058169((3-Amino-phenyl)-carbamic acid 2-piperidin-1-yl-et...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 4(Rat)
Cnrs-Biocis

Curated by ChEMBL
LigandPNGBDBM50058191((4-Amino-phenyl)-carbamic acid 2-piperidin-1-yl-et...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity (Ki+/-SEM) against 5-hydroxytryptamine 4 receptor from cheng Prusoff equation by using [3H]GR-113808 in rat striatumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed