Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50007408
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50029781((R)-(+)-N-{3-[5-(4-fluorobenzyl)thien-2-yl]-1-meth...)
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062675(5-{4-[5-(4-Fluoro-benzyl)-thiophen-2-yl]-but-3-yny...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062676(3,4-Dihydroxy-5-[4-(2-phenylsulfanylmethyl-phenyl)...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062678(3,4-Dihydroxy-5-(4-naphthalen-1-yl-but-3-ynyl)-5H-...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50062677(5-{4-[((Z)-2-Hex-2-enyl)-phenyl]-but-3-ynyl}-3,4-d...)
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Oxis International

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 isolated from ram (sheep) seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Oxis International

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 2 obtained from sheep placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rat)
Oxis International

Curated by ChEMBL
LigandPNGBDBM50000540(1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazo...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase obtained from rat basophilic leukemia cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Oxis International

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 2.40E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 1 isolated from ram (sheep) seminal vesicleMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Oxis International

Curated by ChEMBL
LigandPNGBDBM22360(2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate ...)
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibitory activity against Prostaglandin G/H synthase 2 obtained from sheep placentaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed