Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50010322
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093310(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093310(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for in vitro inhibitory activity against ProthrombinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093302(3-{4-[4-(2,6-Dimethyl-piperidin-1-yl)-butyl]-3-oxo...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093306(3-{4-[5-(2,5-Dimethyl-pyrrolidin-1-yl)-pentyl]-3-o...)
Affinity DataIC50: 48nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093312(3-{4-[6-(2,6-Dimethyl-piperidin-1-yl)-hexyl]-3-oxo...)
Affinity DataIC50: 68nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093309(3-[4-(5-Diisopropylamino-pentyl)-3-oxo-3,4-dihydro...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093299(3-[4-(5-Morpholin-4-yl-pentyl)-3-oxo-3,4-dihydro-2...)
Affinity DataIC50: 240nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093302(3-{4-[4-(2,6-Dimethyl-piperidin-1-yl)-butyl]-3-oxo...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093310(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 330nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093306(3-{4-[5-(2,5-Dimethyl-pyrrolidin-1-yl)-pentyl]-3-o...)
Affinity DataIC50: 760nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093308(2-(3-Aminomethyl-phenyl)-4-[5-(2,6-dimethyl-piperi...)
Affinity DataIC50: 840nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093310(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 890nMAssay Description:Compound was tested for in vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093306(3-{4-[5-(2,5-Dimethyl-pyrrolidin-1-yl)-pentyl]-3-o...)
Affinity DataIC50: 910nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 990nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093299(3-[4-(5-Morpholin-4-yl-pentyl)-3-oxo-3,4-dihydro-2...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093302(3-{4-[4-(2,6-Dimethyl-piperidin-1-yl)-butyl]-3-oxo...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093309(3-[4-(5-Diisopropylamino-pentyl)-3-oxo-3,4-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093309(3-[4-(5-Diisopropylamino-pentyl)-3-oxo-3,4-dihydro...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093320(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093301(3-[4-(5-Dihexylamino-pentyl)-3-oxo-3,4-dihydro-2H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093318(4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093301(3-[4-(5-Dihexylamino-pentyl)-3-oxo-3,4-dihydro-2H-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093312(3-{4-[6-(2,6-Dimethyl-piperidin-1-yl)-hexyl]-3-oxo...)
Affinity DataIC50: 2.10E+3nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093299(3-[4-(5-Morpholin-4-yl-pentyl)-3-oxo-3,4-dihydro-2...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093301(3-[4-(5-Dihexylamino-pentyl)-3-oxo-3,4-dihydro-2H-...)
Affinity DataIC50: 2.20E+3nMAssay Description:Compound was tested for in vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093301(3-[4-(5-Dihexylamino-pentyl)-3-oxo-3,4-dihydro-2H-...)
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093311(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 2.80E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093317(3-[4-(5-Amino-pentyl)-3-oxo-3,4-dihydro-2H-benzo[1...)
Affinity DataIC50: 4.30E+3nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093314(4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-2-(4-me...)
Affinity DataIC50: 4.90E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093319(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 5.60E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093312(3-{4-[6-(2,6-Dimethyl-piperidin-1-yl)-hexyl]-3-oxo...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093317(3-[4-(5-Amino-pentyl)-3-oxo-3,4-dihydro-2H-benzo[1...)
Affinity DataIC50: 6.30E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093308(2-(3-Aminomethyl-phenyl)-4-[5-(2,6-dimethyl-piperi...)
Affinity DataIC50: 7.80E+3nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093318(4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 7.90E+3nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093310(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 8.40E+3nMAssay Description:Compound was tested for in vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093312(3-{4-[6-(2,6-Dimethyl-piperidin-1-yl)-hexyl]-3-oxo...)
Affinity DataIC50: 1.20E+4nMAssay Description:Compound was tested for in vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine protease 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093318(4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 1.30E+4nMAssay Description:In vitro inhibitory activity against trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093304(2-(2-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1...)
Affinity DataIC50: 1.60E+4nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093303(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093313(3-[3-Oxo-4-(5-piperidin-1-yl-pentyl)-3,4-dihydro-2...)
Affinity DataIC50: 2.10E+4nMAssay Description:Compound was tested for in vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093310(3-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 2.30E+4nMAssay Description:Compound was tested for in vitro inhibitory activity against activated protein CMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093305(2-(4-Chloro-phenyl)-4-[5-(2,6-dimethyl-piperidin-1...)
Affinity DataIC50: 2.30E+4nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093308(2-(3-Aminomethyl-phenyl)-4-[5-(2,6-dimethyl-piperi...)
Affinity DataIC50: 2.50E+4nMAssay Description:Compound was tested for in vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093315(2-(3,4-Dichloro-phenyl)-4-[5-(2,6-dimethyl-piperid...)
Affinity DataIC50: 2.60E+4nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093300(4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-2-pheny...)
Affinity DataIC50: 2.70E+4nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093316(4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-2-p-tol...)
Affinity DataIC50: 2.80E+4nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093307(4-{4-[5-(2,6-Dimethyl-piperidin-1-yl)-pentyl]-3-ox...)
Affinity DataIC50: 3.40E+4nMAssay Description:In vitro inhibition of coagulation factor Xa.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50093302(3-{4-[4-(2,6-Dimethyl-piperidin-1-yl)-butyl]-3-oxo...)
Affinity DataIC50: 3.80E+4nMAssay Description:Compound was tested for in vitro inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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