Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50010514
TargetLanosterol synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 35nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095598([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(1-py...)
Affinity DataIC50: 37nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095601([4-(1-Aza-bicyclo[2.2.2]oct-3-yloxy)-phenyl]-(4-ch...)
Affinity DataIC50: 58nMAssay Description:In vitro percent inhibitory activity of the compound against rat microsomal OSC enzyme at 1 uM concentrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095600([4-(4-Iodo-benzenesulfonyl)-piperazin-1-yl]-(3,4,5...)
Affinity DataIC50: 82nMAssay Description:In vitro inhibitory activity of the compound against rat microsomal 2,3-Oxidosqualene cyclase-Lanosterol synthase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095599({4-[4-(4,5-Dihydro-oxazol-2-yl)-benzylidene]-piper...)
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity of the compound against rat microsomal 2,3-Oxidosqualene lanosterol cyclase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095597([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-[1-(2...)
Affinity DataIC50: 112nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095598([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(1-py...)
Affinity DataIC50: 116nMAssay Description:Compound was tested for its inhibition against rat OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095595((4-Benzenesulfonyl-piperazin-1-yl)-(3,4,5,6-tetrah...)
Affinity DataIC50: 143nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095596([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(3,4,...)
Affinity DataIC50: 161nMAssay Description:Compound was tested for its inhibition against human OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095596([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-(3,4,...)
Affinity DataIC50: 228nMAssay Description:In vitro inhibitory activity of the compound against rat microsomal 2,3-Oxidosqualene lanosterol cyclase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095595((4-Benzenesulfonyl-piperazin-1-yl)-(3,4,5,6-tetrah...)
Affinity DataIC50: 326nMAssay Description:In vitro inhibitory activity of the compound against rat microsomal 2,3-Oxidosqualene lanosterol cyclase (OSC)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50095597([4-(4-Bromo-benzenesulfonyl)-piperazin-1-yl]-[1-(2...)
Affinity DataIC50: 398nMAssay Description:Compound was tested for its inhibition against rat OSC enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed