Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50010998
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101077((2S,3S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-phosphon...)
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101077((2S,3S)-2-((S)-2-{(S)-2-[(S)-2-Amino-3-(4-phosphon...)
Affinity DataIC50: 1.33E+3nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101081((S)-4-((S)-2-{2-Acetylamino-3-[4-(2-methoxycarbony...)
Affinity DataIC50: 2.30E+3nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101078((S)-4-{2-Acetylamino-3-[4-(2-methoxycarbonyl-2-oxo...)
Affinity DataIC50: 8.60E+3nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101079(4-((S)-1-Carbamoyl-2-methyl-butylcarbamoyl)-4-((S)...)
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101083((S)-4-((1S,2S)-1-Carbamoyl-2-methyl-butylcarbamoyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101080(2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101082(3-(2-{(S)-1-[(S)-1-((S)-(S)-1-Carbamoyl-2-methyl-b...)
Affinity DataIC50: 2.50E+5nMAssay Description:Binding affinity for wild type Src SH2 domain using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101080(2,2-Dihydroxy-3-oxo-3-phenyl-propionic acid methyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101078((S)-4-{2-Acetylamino-3-[4-(2-methoxycarbonyl-2-oxo...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101081((S)-4-((S)-2-{2-Acetylamino-3-[4-(2-methoxycarbony...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101079(4-((S)-1-Carbamoyl-2-methyl-butylcarbamoyl)-4-((S)...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101083((S)-4-((1S,2S)-1-Carbamoyl-2-methyl-butylcarbamoyl...)
Affinity DataIC50: 1.00E+6nMAssay Description:Binding affinity for Cys188Ala Src SH2 domain mutant using BIAcore binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed