Compile Data Set for Download or QSAR
Report error Found 64 Enz. Inhib. hit(s) with all data for entry = 50011946
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataEC50:  3.40E+3nMAssay Description:Inhibition of geranylgeranylation of Rap1a in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataEC50:  6.90nMAssay Description:Inhibition of HDJ2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataEC50:  28nMAssay Description:Inhibition of HDJ2 farnesylation in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataEC50:  800nMAssay Description:Inhibition of geranylgeranylation of Rap1a in PSN-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataIC50: 0.170nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112387(3-oxo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22...)
Affinity DataIC50: 0.190nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112387(3-oxo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22...)
Affinity DataIC50: 0.25nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataIC50: 0.480nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112372(17-(5,5,5-trifluoro-1-pentynyl)-19-oxa-2,5,10,12-t...)
Affinity DataIC50: 0.810nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112381(17-(4-trifluoromethylphenyl)-19-oxa-2,5,10,12-tetr...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112390(17-bromo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112375(1-(3-Chloro-phenyl)-4-[3-(2-methoxy-4'-trifluorome...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112390(17-bromo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2...)
Affinity DataIC50: 2nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097071(4-{5-[4-(3-Chloro-phenyl)-3-oxo-piperazin-1-ylmeth...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50112381(17-(4-trifluoromethylphenyl)-19-oxa-2,5,10,12-tetr...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112372(17-(5,5,5-trifluoro-1-pentynyl)-19-oxa-2,5,10,12-t...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112377(1-(3-Chloro-phenyl)-4-[3-(4'-trifluoromethyl-biphe...)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112372(17-(5,5,5-trifluoro-1-pentynyl)-19-oxa-2,5,10,12-t...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112388(19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22,5.114...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112373(4-[3-(4'-Chloro-biphenyl-4-ylmethyl)-3H-imidazol-4...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112378(17-butyl-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112374(4-(3-Biphenyl-4-ylmethyl-3H-imidazol-4-ylmethyl)-1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112375(1-(3-Chloro-phenyl)-4-[3-(2-methoxy-4'-trifluorome...)
Affinity DataIC50: 12nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112376(1-(3-Chloro-phenyl)-4-{3-[6-(4-trifluoromethyl-phe...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112382(1-(3-Chloro-phenyl)-4-[3-(4'-fluoro-biphenyl-4-ylm...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112381(17-(4-trifluoromethylphenyl)-19-oxa-2,5,10,12-tetr...)
Affinity DataIC50: 16nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112387(3-oxo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22...)
Affinity DataIC50: 16nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112392(4-[3-(3'-Chloro-biphenyl-4-ylmethyl)-3H-imidazol-4...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112389(1-(3-Chloro-phenyl)-4-{3-[6-(4-chloro-phenyl)-pyri...)
Affinity DataIC50: 19nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112377(1-(3-Chloro-phenyl)-4-[3-(4'-trifluoromethyl-biphe...)
Affinity DataIC50: 29nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112385(1-(3-Chloro-phenyl)-4-[3-(3',5'-dichloro-biphenyl-...)
Affinity DataIC50: 35nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112391(1-(3-Chloro-phenyl)-4-{3-[6-(4-trifluoromethoxy-ph...)
Affinity DataIC50: 52nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112383(17-(5,5,5-trifluoropentyl)-19-oxa-2,5,10,12-tetraa...)
Affinity DataIC50: 60nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112375(1-(3-Chloro-phenyl)-4-[3-(2-methoxy-4'-trifluorome...)
Affinity DataIC50: 70nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50097071(4-{5-[4-(3-Chloro-phenyl)-3-oxo-piperazin-1-ylmeth...)
Affinity DataIC50: 95nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50112377(1-(3-Chloro-phenyl)-4-[3-(4'-trifluoromethyl-biphe...)
Affinity DataIC50: 140nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112379(1-(3-Chloro-phenyl)-4-{2-[3-(2-methoxy-4'-trifluor...)
Affinity DataIC50: 151nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112376(1-(3-Chloro-phenyl)-4-{3-[6-(4-trifluoromethyl-phe...)
Affinity DataIC50: 159nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112390(17-bromo-19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2...)
Affinity DataIC50: 161nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112373(4-[3-(4'-Chloro-biphenyl-4-ylmethyl)-3H-imidazol-4...)
Affinity DataIC50: 193nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112373(4-[3-(4'-Chloro-biphenyl-4-ylmethyl)-3H-imidazol-4...)
Affinity DataIC50: 210nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112389(1-(3-Chloro-phenyl)-4-{3-[6-(4-chloro-phenyl)-pyri...)
Affinity DataIC50: 250nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112384(1-(3-Chloro-phenyl)-4-[3-(2'-methoxy-4'-trifluorom...)
Affinity DataIC50: 392nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112386(1-(3-Chloro-phenyl)-4-[3-(3'-trifluoromethyl-biphe...)
Affinity DataIC50: 410nMAssay Description:Inhibition of Farnesyltransferase catalyzed incorporation of [3H]-FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112385(1-(3-Chloro-phenyl)-4-[3-(3',5'-dichloro-biphenyl-...)
Affinity DataIC50: 437nMAssay Description:Displacement of radiolabeled FTI from Farnesyltransferase in v-Ha-ras-transformed Rat1 cells.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112388(19-oxa-2,5,10,12-tetraazahexacyclo[18.6.2.22,5.114...)
Affinity DataIC50: 509nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112376(1-(3-Chloro-phenyl)-4-{3-[6-(4-trifluoromethyl-phe...)
Affinity DataIC50: 509nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50112391(1-(3-Chloro-phenyl)-4-{3-[6-(4-trifluoromethoxy-ph...)
Affinity DataIC50: 560nMAssay Description:Inhibition of the human Geranylgeranyl transferase type I catalyzed incorporation of [3H]GGPP into a biotinylated peptide corresponding to the C-term...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 64 total ) | Next | Last >>
Jump to: