Compile Data Set for Download or QSAR
Report error Found 114 Enz. Inhib. hit(s) with all data for entry = 50012933
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124496(Pyrazin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyrid...)
Affinity DataIC50: 0.400nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124474(Pyridin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyrid...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124465(Pyridin-2-yl-carbamic acid 4-[5-(2-methoxy-phenoxy...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124453(Pyrazin-2-yl-carbamic acid 4-[5-(2-methoxy-phenoxy...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124487(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124498(Pyridin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyrid...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124481(5-Methyl-pyridine-2-sulfonic acid [2-(2-hydroxymet...)
Affinity DataIC50: 11nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124495(Pyridin-4-yl-carbamic acid 4-[5-(2-methoxy-phenoxy...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124507(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124462(4-tert-Butyl-N-[6-(4-methoxy-but-2-ynyloxy)-5-(2-m...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124470(Phenyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124494(5-Methyl-pyridine-2-sulfonic acid {5-(2-methoxy-ph...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124496(Pyrazin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyrid...)
Affinity DataIC50: 13nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124492(Pyrazin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyrid...)
Affinity DataIC50: 14nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124504(5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy...)
Affinity DataIC50: 16nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124459(Butyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-s...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124463(5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-bu...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124503(Phenyl-carbamic acid 4-[5-(2-methoxy-phenoxy)-6-(5...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124456(Pyridin-3-yl-carbamic acid 4-[5-(2-methoxy-phenoxy...)
Affinity DataIC50: 21nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124466(5-Methyl-pyridine-2-sulfonic acid [6-(4-hydroxy-bu...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124486(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)
Affinity DataIC50: 22nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124476(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)
Affinity DataIC50: 23nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124493(5-Isopropyl-pyridine-2-sulfonic acid [2-(2-hydroxy...)
Affinity DataIC50: 24nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124483(5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy...)
Affinity DataIC50: 26nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124482(5-Isopropyl-pyridine-2-sulfonic acid {5-(2-methoxy...)
Affinity DataIC50: 27nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124470(Phenyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-...)
Affinity DataIC50: 28nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124485(Phenyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-...)
Affinity DataIC50: 32nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124485(Phenyl-carbamic acid 4-[6-(5-isopropyl-pyridine-2-...)
Affinity DataIC50: 35nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124473(4-tert-Butyl-N-[2-(2-hydroxymethyl-pyridin-4-yl)-5...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061101(4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyph...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124474(Pyridin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyrid...)
Affinity DataIC50: 42nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124461(4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-m...)
Affinity DataIC50: 44nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124504(5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy...)
Affinity DataIC50: 49nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124480(4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-m...)
Affinity DataIC50: 50nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124471(4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-m...)
Affinity DataIC50: 51nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124457(5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy...)
Affinity DataIC50: 53nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124488(4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-pent-2-yny...)
Affinity DataIC50: 59nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124454(4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-2-[2-(5-oxo-...)
Affinity DataIC50: 66nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124483(5-Isopropyl-pyridine-2-sulfonic acid [6-(4-hydroxy...)
Affinity DataIC50: 77nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124506(4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-6-prop-2-yny...)
Affinity DataIC50: 84nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124502(4-tert-Butyl-N-[6-but-2-ynyloxy-5-(2-methoxy-pheno...)
Affinity DataIC50: 85nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124468(5-Methyl-pyridine-2-sulfonic acid [5-(2-methoxy-ph...)
Affinity DataIC50: 94nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124505(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)
Affinity DataIC50: 96nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124497(4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-prop-2-yny...)
Affinity DataIC50: 97nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124473(4-tert-Butyl-N-[2-(2-hydroxymethyl-pyridin-4-yl)-5...)
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124475(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)
Affinity DataIC50: 121nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin receptor type B(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124498(Pyridin-2-yl-carbamic acid 4-[6-(5-isopropyl-pyrid...)
Affinity DataIC50: 123nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETB receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124461(4-tert-Butyl-N-[6-(4-hydroxy-but-2-ynyloxy)-5-(2-m...)
Affinity DataIC50: 125nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124464(5-Isopropyl-pyridine-2-sulfonic acid [5-(2-methoxy...)
Affinity DataIC50: 125nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEndothelin-1 receptor(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50124460(4-tert-Butyl-N-[5-(2-methoxy-phenoxy)-6-(4-phenoxy...)
Affinity DataIC50: 139nMAssay Description:In vitro inhibitory concentration required against [125I]ET1 binding to membranes of CHO cells expressing human ETA receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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