Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50013073
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404221BDBM50404221(CHEMBL285139)
Affinity DataEC50:  0.300nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126158BDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataEC50:  0.360nMAssay Description:Effective concentration of progesterone receptor agonist induction of alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404224BDBM50404224(CHEMBL27379)
Affinity DataEC50:  0.5nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404239BDBM50404239(CHEMBL28031)
Affinity DataEC50:  0.5nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067678BDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  0.5nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404228BDBM50404228(CHEMBL28161)
Affinity DataEC50:  0.800nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404222BDBM50404222(CHEMBL417475)
Affinity DataEC50:  1nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404215BDBM50404215(CHEMBL27818)
Affinity DataEC50:  1.40nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404227BDBM50404227(CHEMBL28102)
Affinity DataEC50:  1.40nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404235BDBM50404235(CHEMBL25021)
Affinity DataEC50:  1.60nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404229BDBM50404229(CHEMBL24089)
Affinity DataEC50:  1.60nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404218BDBM50404218(CHEMBL27766)
Affinity DataEC50:  1.90nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404217BDBM50404217(CHEMBL280767)
Affinity DataEC50:  1.90nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375837BDBM50375837(CHEMBL270976)
Affinity DataEC50:  2nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404219BDBM50404219(CHEMBL283337)
Affinity DataEC50:  2.5nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404238BDBM50404238(CHEMBL286029)
Affinity DataEC50:  2.60nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404216BDBM50404216(CHEMBL282774)
Affinity DataEC50:  4.20nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404237BDBM50404237(CHEMBL26997)
Affinity DataEC50:  4.30nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404223BDBM50404223(CHEMBL280805)
Affinity DataEC50:  5nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404234BDBM50404234(CHEMBL25061)
Affinity DataEC50:  5.30nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404226BDBM50404226(CHEMBL287428)
Affinity DataEC50:  5.40nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067678BDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  6.10nMAssay Description:Effective concentration against Androgen receptor in mouse fibroblast L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126158BDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataIC50: 7.43nMAssay Description:Inhibitory progestational activity on oral administration in uterine C3 modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404236BDBM50404236(CHEMBL28213)
Affinity DataEC50:  7.70nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404233BDBM50404233(CHEMBL283759)
Affinity DataEC50:  9.80nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067678BDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  10nMAssay Description:Effective concentration against glucocorticoid receptor in human lung A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067678BDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataIC50: 11nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404213BDBM50404213(CHEMBL26770)
Affinity DataEC50:  15nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126158BDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataIC50: 16nMAssay Description:Inhibition of 3 nM [3H]R5020 binding to progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404212BDBM50404212(CHEMBL27052)
Affinity DataEC50:  24nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404220BDBM50404220(CHEMBL25261)
Affinity DataEC50:  29nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126158BDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against glucocorticoid receptor in human lung A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121180BDBM50121180(5'-(3-chlorophenyl)spiro[cyclohexane-1,3'-indol]-2...)
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067678BDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataIC50: 67.3nMAssay Description:Inhibitory progestational activity on oral administration in uterine C3 modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404214BDBM50404214(CHEMBL412874)
Affinity DataEC50:  71nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404222BDBM50404222(CHEMBL417475)
Affinity DataIC50: 92.5nMAssay Description:Inhibitory progestational activity on oral administration in uterine C3 modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404232BDBM50404232(CHEMBL25430)
Affinity DataEC50:  200nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50375837BDBM50375837(CHEMBL270976)
Affinity DataIC50: 942nMAssay Description:Inhibitory progestational activity on oral administration in uterine C3 modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404229BDBM50404229(CHEMBL24089)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibitory progestational activity on oral administration in uterine C3 modelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404230BDBM50404230(CHEMBL26755)
Affinity DataEC50:  1.20E+3nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404225BDBM50404225(CHEMBL25429)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404211BDBM50404211(CHEMBL25182)
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration of progesterone receptor agonist induction of alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404211BDBM50404211(CHEMBL25182)
Affinity DataEC50: >3.00E+3nMAssay Description:Effective concentration of progesterone receptor agonist induction of alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50404231BDBM50404231(CHEMBL28256)
Affinity DataEC50: >3.00E+3nMAssay Description:Inhibitory activity against progesterone receptor induced alkaline phosphatase activity in human T47D breast carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126158BDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against glucocorticoid receptor in human lung A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126158BDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration against Androgen receptor in mouse fibroblast L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126158BDBM50126158(3-fluoro-5-(2'-thioxo-1',2'-dihydrospiro[cyclohexa...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against Androgen receptor in mouse fibroblast L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed