Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50019086
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50615191(CHEMBL5271804)
Affinity DataIC50: 30nMAssay Description:Inhibition of PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of [33P]gamma-ATP and ATP by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50615191(CHEMBL5271804)
Affinity DataIC50: 40nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of [33P]gamma-ATP and ATP by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 208nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50511422(CHEMBL4446338)
Affinity DataIC50: 950nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50615192(CHEMBL4284012)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of PI5P4Kalpha in human HeLa cells pre-incubated for 1 hr followed by ATP addition measured after 90 mins by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM60983(I-OMe-Tyrphostin AG 538 | (E)-2-[(3,4-dihydroxyphe...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo reagent based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 beta(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human full length PI5P4Kbeta expressed in Escherichia coli BL21(DE3) pre-incubated for 15 mins followed by ATP addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPhosphatidylinositol 5-phosphate 4-kinase type-2 alpha(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50511409(Imanixil)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human full length PI5P4Kalpha expressed in Escherichia coli BL21(DE3) pre-incubated for 15 mins followed by ATP addition measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed