Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50034981
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366571(CHEMBL1788261)
Affinity DataIC50: 1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069286(5-Chloro-4-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...)
Affinity DataIC50: 1.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 2.5nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070570(5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Affinity DataIC50: 2.90nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366569(CHEMBL1788262)
Affinity DataIC50: 4.5nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50450877(CHEMBL2093035)
Affinity DataIC50: 4.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069288(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50: 4.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069287(5-Chloro-N-(1-ethyl-azepan-3-yl)-2-methoxy-4-methy...)
Affinity DataIC50: 6.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50450876(CHEMBL2093034)
Affinity DataIC50: 7nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069282(4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...)
Affinity DataIC50: 8.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069290(4-Amino-5-chloro-N-(1,4-dimethyl-[1,4]diazepan-6-y...)
Affinity DataIC50: 9.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50450878(CHEMBL2093036)
Affinity DataIC50: 10nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069287(5-Chloro-N-(1-ethyl-azepan-3-yl)-2-methoxy-4-methy...)
Affinity DataIC50: 11nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366568(CHEMBL1788260)
Affinity DataIC50: 12nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366570(CHEMBL1788263)
Affinity DataIC50: 19nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069289(4-Amino-5-chloro-2-methoxy-N-(1-methyl-4-propyl-[1...)
Affinity DataIC50: 24nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069284(5-Chloro-4-ethylamino-N-(1-ethyl-azepan-3-yl)-2-me...)
Affinity DataIC50: 25nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069281(4-Amino-5-chloro-N-(1-ethyl-azepan-3-yl)-2-methoxy...)
Affinity DataIC50: 33nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50070570(5-Chloro-N-((R)-1-ethyl-4-methyl-[1,4]diazepan-6-y...)
Affinity DataIC50: 35nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069291(4-Amino-5-chloro-2-methoxy-N-(1-methyl-azepan-3-yl...)
Affinity DataIC50: 36nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069285(4-Amino-5-chloro-2-methoxy-N-(1-propyl-azepan-3-yl...)
Affinity DataIC50: 37nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069281(4-Amino-5-chloro-N-(1-ethyl-azepan-3-yl)-2-methoxy...)
Affinity DataIC50: 39nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069284(5-Chloro-4-ethylamino-N-(1-ethyl-azepan-3-yl)-2-me...)
Affinity DataIC50: 50nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069285(4-Amino-5-chloro-2-methoxy-N-(1-propyl-azepan-3-yl...)
Affinity DataIC50: 57nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069288(5-Chloro-N-(1-ethyl-4-methyl-[1,4]diazepan-6-yl)-2...)
Affinity DataIC50: 61nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366568(CHEMBL1788260)
Affinity DataIC50: 87nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069283(4-Amino-5-chloro-N-(1-isopropyl-azepan-3-yl)-2-met...)
Affinity DataIC50: 87nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366569(CHEMBL1788262)
Affinity DataIC50: 97nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50241107(CHEMBL219916 | 5-chloro-1-(1-(3-(2-oxo-2,3-dihydro...)
Affinity DataIC50: 100nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069282(4-Amino-5-chloro-N-(1-ethyl-4-methyl-[1,4]diazepan...)
Affinity DataIC50: 127nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366570(CHEMBL1788263)
Affinity DataIC50: 134nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069286(5-Chloro-4-ethylamino-N-(1-ethyl-4-methyl-[1,4]dia...)
Affinity DataIC50: 181nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069289(4-Amino-5-chloro-2-methoxy-N-(1-methyl-4-propyl-[1...)
Affinity DataIC50: 218nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069291(4-Amino-5-chloro-2-methoxy-N-(1-methyl-azepan-3-yl...)
Affinity DataIC50: 230nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366571(CHEMBL1788261)
Affinity DataIC50: 320nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50450877(CHEMBL2093035)
Affinity DataIC50: 367nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataIC50: 480nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50450876(CHEMBL2093034)
Affinity DataIC50: 517nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069283(4-Amino-5-chloro-N-(1-isopropyl-azepan-3-yl)-2-met...)
Affinity DataIC50: 640nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM48320(SMR000058471 | METOCLOPRAMIDE | METOCLOPRAMIDE HYD...)
Affinity DataIC50: 880nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50069290(4-Amino-5-chloro-N-(1,4-dimethyl-[1,4]diazepan-6-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for binding affinity against Dopamine receptor D2 in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM85330(NSC_68647 | CAS_68647 | ONDANSETRON | Ondansetron ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Rat)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50450878(CHEMBL2093036)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed