Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50035133
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101114(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-sulfon...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101129(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carbox...)
Affinity DataIC50: 14nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101124(sodium 8-fluoro-6-oxo-5,6-dihydrophenanthridine-3-...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101105(CHEMBL540525 | CHEMBL417002 | 6-Oxo-5,6-dihydro-ph...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against purified recombinant human Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101108(Trimethyl-[(6-oxo-5,6-dihydro-phenanthridin-2-ylca...)
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101104(2-Chloro-N-(10-methyl-6-oxo-3-trifluoromethyl-5,6-...)
Affinity DataIC50: 33nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101118(6-Oxo-5,6-dihydro-phenanthridine-3-carboxylic acid...)
Affinity DataIC50: 35nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101105(CHEMBL540525 | CHEMBL417002 | 6-Oxo-5,6-dihydro-ph...)
Affinity DataIC50: 36nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101103(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carbox...)
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101110(2-Amino-10-methyl-3-trifluoromethyl-5H-phenanthrid...)
Affinity DataIC50: 44nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101102(sodium 6-oxo-5,6-dihydrophenanthridine-3-carboxyla...)
Affinity DataIC50: 57nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101116(3-Fluoro-10-methyl-5H-phenanthridin-6-one | CHEMBL...)
Affinity DataIC50: 92nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101126(10-Methyl-2-nitro-3-trifluoromethyl-5H-phenanthrid...)
Affinity DataIC50: 136nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101125(8-Fluoro-6-oxo-5,6-dihydro-phenanthridine-3-carbox...)
Affinity DataIC50: 150nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101127(2-Nitro-5H-phenanthridin-6-one | CHEMBL48391)
Affinity DataIC50: 156nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50200497(2-aminophenanthridin-6(5H)-one | 2-Amino-5H-phenan...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101115(2,3-Diamino-5H-phenanthridin-6-one | CHEMBL45764)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101113(6-Oxo-5,6-dihydro-phenanthridine-3-carboxylic acid...)
Affinity DataIC50: 184nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101120(Trimethyl-[(3-methyl-6-oxo-5,6-dihydro-phenanthrid...)
Affinity DataIC50: 195nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101121(3,8-Dichloro-5H-phenanthridin-6-one | CHEMBL298450)
Affinity DataIC50: 240nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101123(4-Amino-5H-phenanthridin-6-one | CHEMBL298064)
Affinity DataIC50: 312nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM27500(Phenanthridone | 5H-Phenanthridin-6-one (PTD) | 5H...)
Affinity DataIC50: 520nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101119(6-Oxo-5,6-dihydro-phenanthridine-1-carboxylic acid...)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101109(3,8-Diamino-5H-phenanthridin-6-one | CHEMBL47840)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101117(4-Nitro-5H-phenanthridin-6-one | CHEMBL45904)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101111(6-Oxo-5,6-dihydro-phenanthridine-2-sulfonic acid (...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101122(3,8-Dinitro-5H-phenanthridin-6-one | CHEMBL47846)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101130(6-Oxo-5,6-dihydro-phenanthridine-10-carboxylic aci...)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101107(disodium 6-oxo-5,6-dihydrophenanthridine-3,8-disul...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against purified recombinant human poly (ADP-ribose) polymerase-1 (PARP1)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed