Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50035631
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50006906(CHEMBL23977 | 2-{4-[(2-Amino-4-oxo-3,4-dihydro-qui...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022282(2-{4-[(2-Amino-4-hydroxy-7,8-dihydro-pteridin-6-yl...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022280(4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-prop-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008291(CHEMBL280145 | 2-{4-[(2-Amino-4-oxo-1,4-dihydro-pt...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022283(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pterid...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity against dihydrofolate reductase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50367343(Folacin | FOLIC ACID | (2S)-2-[[4-[(2-amino-4-oxo-...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022280(4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-prop-2-...)
Affinity DataIC50: 2.90E+5nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022283(2-{4-[(2-Amino-4-hydroxy-5,6,7,8-tetrahydro-pterid...)
Affinity DataIC50: 3.20E+5nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008291(CHEMBL280145 | 2-{4-[(2-Amino-4-oxo-1,4-dihydro-pt...)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022282(2-{4-[(2-Amino-4-hydroxy-7,8-dihydro-pteridin-6-yl...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 6.00E+5nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022281(2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-meth...)
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50008291(CHEMBL280145 | 2-{4-[(2-Amino-4-oxo-1,4-dihydro-pt...)
Affinity DataIC50: 7.50E+5nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50022281(2-{4-[(2-Amino-4-hydroxy-pteridin-6-ylmethyl)-meth...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50008291(CHEMBL280145 | 2-{4-[(2-Amino-4-oxo-1,4-dihydro-pt...)
Affinity DataIC50: 3.00E+6nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50367343(Folacin | FOLIC ACID | (2S)-2-[[4-[(2-amino-4-oxo-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibitory activity against thymidylate synthase in the intact L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed