Compile Data Set for Download or QSAR
Report error Found 75 Enz. Inhib. hit(s) with all data for entry = 50040272
LigandPNGBDBM50391763(CHEMBL2146867)
Affinity DataIC50: 0.760nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391764(CHEMBL2146865)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391760(CHEMBL2146866)
Affinity DataIC50: 3.90nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)
Affinity DataIC50: 5nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391777(CHEMBL2146861)
Affinity DataIC50: 7nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391789(CHEMBL2146757)
Affinity DataIC50: 9nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391776(CHEMBL2146868)
Affinity DataIC50: 12nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391767(CHEMBL2146857)
Affinity DataIC50: 19nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391790(CHEMBL2146852)
Affinity DataIC50: 22nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391775(CHEMBL2146858)
Affinity DataIC50: 23nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)
Affinity DataIC50: 24nMAssay Description:Inhibition of ROMK by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391791(CHEMBL2146853)
Affinity DataIC50: 25nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391762(CHEMBL2146870)
Affinity DataIC50: 26nMAssay Description:Inhibition of ROMK by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50: 30nMAssay Description:Inhibition of ROMK by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391772(CHEMBL2146851)
Affinity DataIC50: 42nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391784(CHEMBL2146854)
Affinity DataIC50: 47nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50: 49nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391770(CHEMBL2146755 | US9073882, 1)
Affinity DataIC50: 52nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391765(CHEMBL2146877)
Affinity DataIC50: 53nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50: 55nMAssay Description:Inhibition of rat ROMK channel expressed in HEk293 cells assessed as inhibition of thallium efflux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391773(CHEMBL2146869)
Affinity DataIC50: 67nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391786(CHEMBL2146874)
Affinity DataIC50: 75nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391789(CHEMBL2146757)
Affinity DataIC50: 79nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391766(CHEMBL2146856)
Affinity DataIC50: 89nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391783(CHEMBL2146876)
Affinity DataIC50: 89nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391762(CHEMBL2146870)
Affinity DataIC50: 89nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391782(CHEMBL2146875)
Affinity DataIC50: 99nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391761(CHEMBL2146878)
Affinity DataIC50: 110nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391786(CHEMBL2146874)
Affinity DataIC50: 120nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391763(CHEMBL2146867)
Affinity DataIC50: 140nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391766(CHEMBL2146856)
Affinity DataIC50: 150nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391785(CHEMBL2146862)
Affinity DataIC50: 150nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50: 170nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391791(CHEMBL2146853)
Affinity DataIC50: 170nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391771(CHEMBL2146754)
Affinity DataIC50: 190nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391760(CHEMBL2146866)
Affinity DataIC50: 240nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391778(CHEMBL2146879 | US9073882, 64)
Affinity DataIC50: 280nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391769(CHEMBL2146872)
Affinity DataIC50: 280nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM73215(VU0277590-7 | 7,13-bis[(4-nitrophenyl)methyl]-1,4,...)
Affinity DataIC50: 290nMAssay Description:Inhibition of ROMKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391768(CHEMBL2146871 | US9073882, 95)
Affinity DataIC50: 300nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391764(CHEMBL2146865)
Affinity DataIC50: 340nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391780(CHEMBL2146881 | US9073882, 62)
Affinity DataIC50: 430nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391768(CHEMBL2146871 | US9073882, 95)
Affinity DataIC50: 430nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391779(CHEMBL2146880)
Affinity DataIC50: 460nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391778(CHEMBL2146879 | US9073882, 64)
Affinity DataIC50: 470nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391779(CHEMBL2146880)
Affinity DataIC50: 550nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391782(CHEMBL2146875)
Affinity DataIC50: 560nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391761(CHEMBL2146878)
Affinity DataIC50: 620nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391780(CHEMBL2146881 | US9073882, 62)
Affinity DataIC50: 670nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50391765(CHEMBL2146877)
Affinity DataIC50: 670nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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