Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50043880
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335231BDBM50335231(NIBR3049 | CHEMBL1650951 | 3-{5-[4-(2-Hydroxy-2-me...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355501BDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355501BDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193995BDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193995BDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50193995BDBM50193995(CP-690550 | 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrro...)
Affinity DataIC50: 11nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447884BDBM50447884(CHEMBL3114786)
Affinity DataIC50: 12nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447883BDBM50447883(CHEMBL3114761)
Affinity DataIC50: 13nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355501BDBM50355501(RUXOLITINIB PHOSPHATE | INCB-018424 | RUXOLITINIB ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153461BDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 17nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447870BDBM50447870(CHEMBL3114774)
Affinity DataIC50: 29nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447868BDBM50447868(CHEMBL3114776)
Affinity DataIC50: 46nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447878BDBM50447878(CHEMBL3114766)
Affinity DataIC50: 128nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447873BDBM50447873(CHEMBL3114771)
Affinity DataIC50: 135nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447886BDBM50447886(CHEMBL3114784)
Affinity DataIC50: 163nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447869BDBM50447869(CHEMBL3114775)
Affinity DataIC50: 179nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447885BDBM50447885(CHEMBL3114785)
Affinity DataIC50: 200nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447872BDBM50447872(CHEMBL3114772)
Affinity DataIC50: 201nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447876BDBM50447876(CHEMBL3114768)
Affinity DataIC50: 278nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447878BDBM50447878(CHEMBL3114766)
Affinity DataIC50: 300nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335231BDBM50335231(NIBR3049 | CHEMBL1650951 | 3-{5-[4-(2-Hydroxy-2-me...)
Affinity DataIC50: 311nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447866BDBM50447866(CHEMBL3114778)
Affinity DataIC50: 408nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447870BDBM50447870(CHEMBL3114774)
Affinity DataIC50: 423nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447868BDBM50447868(CHEMBL3114776)
Affinity DataIC50: 490nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447882BDBM50447882(CHEMBL3114762)
Affinity DataIC50: 497nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447884BDBM50447884(CHEMBL3114786)
Affinity DataIC50: 564nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447863BDBM50447863(CHEMBL3114781)
Affinity DataIC50: 576nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447879BDBM50447879(CHEMBL3114765)
Affinity DataIC50: 576nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447887BDBM50447887(CHEMBL3114783)
Affinity DataIC50: 625nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447883BDBM50447883(CHEMBL3114761)
Affinity DataIC50: 628nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153461BDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 770nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447873BDBM50447873(CHEMBL3114771)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447875BDBM50447875(CHEMBL3114769)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447884BDBM50447884(CHEMBL3114786)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447873BDBM50447873(CHEMBL3114771)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447887BDBM50447887(CHEMBL3114783)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447865BDBM50447865(CHEMBL3114779)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447864BDBM50447864(CHEMBL3114780)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447883BDBM50447883(CHEMBL3114761)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447867BDBM50447867(CHEMBL3114777)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447869BDBM50447869(CHEMBL3114775)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447869BDBM50447869(CHEMBL3114775)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447877BDBM50447877(CHEMBL3114767)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447872BDBM50447872(CHEMBL3114772)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447870BDBM50447870(CHEMBL3114774)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447863BDBM50447863(CHEMBL3114781)
Affinity DataIC50: 2.17E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50153461BDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447885BDBM50447885(CHEMBL3114785)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447887BDBM50447887(CHEMBL3114783)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50447882BDBM50447882(CHEMBL3114762)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
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