Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50045180
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048488(CHEMBL3310158)
Affinity DataEC50:  295nMAssay Description:Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048487(CHEMBL3310157)
Affinity DataEC50:  1.35E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244276(2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benz...)
Affinity DataEC50:  3.24E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048486(CHEMBL3310167)
Affinity DataEC50:  1.74E+4nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048484(CHEMBL3310166)
Affinity DataEC50:  2.57E+4nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048483(CHEMBL3310164)
Affinity DataEC50:  2.40E+4nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048481(CHEMBL3310162)
Affinity DataEC50:  3.47E+4nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048480(CHEMBL3310161)
Affinity DataEC50:  6.31E+3nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048479(CHEMBL3310159)
Affinity DataEC50:  2.51E+4nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM21279(N-(piperidin-1-yl)-1-(2,4-dichlorophenyl)-5-(4-iod...)
Affinity DataEC50:  58nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048489(CHEMBL3310160)
Affinity DataEC50:  1.26E+4nMAssay Description:Antagonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by sc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50160434(AM630 | (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-...)
Affinity DataEC50:  603nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048487(CHEMBL3310157)
Affinity DataEC50:  174nMAssay Description:Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50244276(2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benz...)
Affinity DataEC50:  141nMAssay Description:Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048486(CHEMBL3310167)
Affinity DataEC50:  2.88E+3nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048484(CHEMBL3310166)
Affinity DataEC50:  1.66E+4nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048483(CHEMBL3310164)
Affinity DataEC50:  1.95E+4nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048482(CHEMBL3310163)
Affinity DataEC50:  5.75E+4nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048481(CHEMBL3310162)
Affinity DataEC50:  1.20E+4nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048480(CHEMBL3310161)
Affinity DataEC50:  6.61E+3nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50048479(CHEMBL3310159)
Affinity DataEC50:  3.16E+4nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Julius-Maximilians-Universit£T W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50180022(5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1...)
Affinity DataEC50:  741nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed