Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50049253
TargetSerine/threonine-protein kinase mTOR(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50348452(CHEMBL1801204 | US9102670, 1a | AZD-8055)
Affinity DataIC50: 4nMAssay Description:Inhibition of human N-terminal FLAG-tagged mTOR (1362-end residues) in presence of [gamma33P]ATP after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM35615(pyrazolo pyrimidine, 5u)
Affinity DataIC50: 9nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human N-terminal FLAG-tagged mTOR (1362-end residues) in presence of [gamma33P]ATP after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
LigandPNGBDBM25045(CHEMBL538346 | mTOR Inhibitor, PI103 | PI-103 | 3-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50237534(CHEMBL4091820)
Affinity DataIC50: 62nMAssay Description:Inhibition of human N-terminal FLAG-tagged mTOR (1362-end residues) in presence of [gamma33P]ATP after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50237533(CHEMBL4062346)
Affinity DataIC50: 67nMAssay Description:Inhibition of human N-terminal FLAG-tagged mTOR (1362-end residues) in presence of [gamma33P]ATP after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
LigandPNGBDBM50237534(CHEMBL4091820)
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
LigandPNGBDBM50237533(CHEMBL4062346)
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
LigandPNGBDBM50348452(CHEMBL1801204 | US9102670, 1a | AZD-8055)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using phosphatidylinositol 4,5-bisphosphate as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50343759(1-ethyl-3-(4-(6-(2-hydroxypropan-2-yl)-4-morpholin...)
Affinity DataKi:  3nMAssay Description:Inhibition of human N-terminal FLAG-tagged mTOR (1362-end residues) in presence of [gamma33P]ATP after 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2019
Entry Details Article
PubMed