Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50049258
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50029207(phenethyl 3-(3,4-dihydroxyphenyl)acrylate | caffei...)
Affinity DataIC50: 130nMAssay Description:Inhibition of thapsigargin-stimulated 15-LOX in human primary polymorphonuclear leukocytes using arachidonic acid as substrate preincubated for 5 min...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of 15-LOX in human primary polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50237598(CHEMBL395428 | US11660306, Example Boswellic acid)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of 15-LOX (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed