Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 552
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3604(CHEMBL53711 | 4-[(3-bromophenyl)-amino]-6-(dimethy...)
Affinity DataIC50: 0.00600nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3603(4-N-(3-bromophenyl)-6-N-methylpyrido[3,4-d]pyrimid...)
Affinity DataIC50: 0.00800nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3600(4-N-(3-bromophenyl)pyrido[3,4-d]pyrimidine-4,6-dia...)
Affinity DataIC50: 0.130nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3702(4-[(3-Bromophenyl)amino]-6-[(2,3-dihydroxypropyl)-...)
Affinity DataIC50: 0.180nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3700(4-[(3-Bromophenyl)amino]-6-[(2-hydroxyethyl)amino]...)
Affinity DataIC50: 0.190nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3724(4-N-(3-chlorophenyl)-6-N-methylpyrido[3,4-d]pyrimi...)
Affinity DataIC50: 0.190nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3701(4-[(3-Bromophenyl)amino]-6-[N-(2-hydroxyethyl)-N-m...)
Affinity DataIC50: 0.220nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3722(3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin...)
Affinity DataIC50: 0.270nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3720(2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin...)
Affinity DataIC50: 0.280nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3714(2-{[3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrim...)
Affinity DataIC50: 0.350nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3721(4-[(3-Bromophenyl)amino]-6-[N-(carboxymethyl)methy...)
Affinity DataIC50: 0.440nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3727(6-(Methylamino)-4-[(3-methylphenyl)amino]pyrido[3,...)
Affinity DataIC50: 0.450nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3703(3-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrimidin...)
Affinity DataIC50: 0.560nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3710(4-N-(3-bromophenyl)-6-N-[2-(morpholin-4-yl)ethyl]p...)
Affinity DataIC50: 0.650nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3717(4-[(3-Bromophenyl)amino]-6-[[2-(4-imidazolyl)ethyl...)
Affinity DataIC50: 0.780nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3713(4-[(3-Bromophenyl)amino]-6-[[2-[N,N-bis(2-hydroxye...)
Affinity DataIC50: 0.930nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3711(4-N-(3-bromophenyl)-6-N-[3-(morpholin-4-yl)propyl]...)
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
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PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3725(6-N-methyl-4-N-[3-(trifluoromethyl)phenyl]pyrido[3...)
Affinity DataIC50: 1.10nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3704(4-[(3-Bromophenyl)amino]-6-[[2-(dimethylamino)-eth...)
Affinity DataIC50: 1.10nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3705(4-N-(3-bromophenyl)-6-N-[3-(dimethylamino)propyl]p...)
Affinity DataIC50: 1.20nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3716(4-[(3-Bromophenyl)amino]-6-[[2-(2-pyridyl)ethyl]am...)
Affinity DataIC50: 1.20nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3731(6-N-[2-(1H-imidazol-4-yl)ethyl]-4-N-(3-methylpheny...)
Affinity DataIC50: 1.30nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3729(4-N-(3-methylphenyl)-6-N-[2-(morpholin-4-yl)ethyl]...)
Affinity DataIC50: 1.5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3715(4-[(3-Bromophenyl)amino]-6-[(3-pyridyl)methylamino...)
Affinity DataIC50: 1.5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3718(4-[(3-Bromophenyl)amino]-6-[[3-(1-imidazolyl)propy...)
Affinity DataIC50: 1.70nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3708(2-{[2-({4-[(3-bromophenyl)amino]pyrido[3,4-d]pyrim...)
Affinity DataIC50: 1.70nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3730(4-[(3-Methylphenyl)amino]-6-[[3-(4-morpholino)prop...)
Affinity DataIC50: 1.80nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3706(4-[(3-Bromophenyl)amino]-6-[[4-(dimethylamino)buty...)
Affinity DataIC50: 1.80nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3728(6-N,6-N-dimethyl-4-N-(3-methylphenyl)pyrido[3,4-d]...)
Affinity DataIC50: 2.80nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3726(4-N-(3-methylphenyl)pyrido[3,4-d]pyrimidine-4,6-di...)
Affinity DataIC50: 3.10nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3712(4-[(3-Bromophenyl)amino]-6-[[3-(4-methyl-1-piperaz...)
Affinity DataIC50: 3.90nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3707(4-N-(3-bromophenyl)-6-N-[3-(diethylamino)-2-hydrox...)
Affinity DataIC50: 4.60nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3719(4-[(3-Bromophenyl)amino]-6-(4-methyl-1-piperazinyl...)
Affinity DataIC50: 6.40nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3709(4-N-(3-bromophenyl)-6-N-[2-(dimethylamino)ethyl]-6...)
Affinity DataIC50: 8.10nMpH: 7.4 T: 2°CAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3607(6-N-methyl-4-N-phenylpyrido[3,4-d]pyrimidine-4,6-d...)
Affinity DataIC50: 9nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Auckland

LigandPNGBDBM3732(4-N-(3-bromophenyl)-2-methyl-6-N-[2-(morpholin-4-y...)
Affinity DataIC50: 117nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed