Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50020493
LigandChemical structure of BindingDB Monomer ID 50630490BDBM50630490(CHEMBL5408007)
Affinity DataIC50: 0.150nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630495BDBM50630495(CHEMBL5409389)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630492BDBM50630492(CHEMBL5403928)
Affinity DataIC50: 0.560nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630491BDBM50630491(CHEMBL5423228)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630493BDBM50630493(CHEMBL5427865)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630489BDBM50630489(CHEMBL5411537)
Affinity DataIC50: 1nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630488BDBM50630488(CHEMBL5438164)
Affinity DataIC50: 2nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630485BDBM50630485(CHEMBL5408252)
Affinity DataIC50: 8nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630487BDBM50630487(CHEMBL5423220)
Affinity DataIC50: 14nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630483BDBM50630483(CHEMBL5399814)
Affinity DataIC50: 23nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50155926BDBM50155926(CHEMBL3183703)
Affinity DataIC50: 30nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50553944BDBM50553944(CHEMBL4780624)
Affinity DataIC50: 36nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630496BDBM50630496(CHEMBL5423530)
Affinity DataIC50: 66nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630494BDBM50630494(CHEMBL5397039)
Affinity DataIC50: 120nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630484BDBM50630484(CHEMBL5432079)
Affinity DataIC50: 190nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630486BDBM50630486(CHEMBL5440114)
Affinity DataIC50: 270nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630477BDBM50630477(CHEMBL5427193)
Affinity DataIC50: 440nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630465BDBM50630465(CHEMBL5407505)
Affinity DataIC50: 440nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630475BDBM50630475(CHEMBL5417052)
Affinity DataIC50: 590nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630479BDBM50630479(CHEMBL5402869)
Affinity DataIC50: 810nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630474BDBM50630474(CHEMBL5420080)
Affinity DataIC50: 930nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630472BDBM50630472(CHEMBL5404989)
Affinity DataIC50: 970nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630481BDBM50630481(CHEMBL5432654)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630473BDBM50630473(CHEMBL5409945)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630476BDBM50630476(CHEMBL5436264)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50553912BDBM50553912(CHEMBL4795130)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630469BDBM50630469(CHEMBL5426519)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630482BDBM50630482(CHEMBL5406685)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630478BDBM50630478(CHEMBL5433230)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630468BDBM50630468(CHEMBL5424149)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630480BDBM50630480(CHEMBL5422068)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630470BDBM50630470(CHEMBL5433625)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630471BDBM50630471(CHEMBL5416016)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630464BDBM50630464(CHEMBL5408846)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630466BDBM50630466(CHEMBL5408441)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50630467BDBM50630467(CHEMBL5420131)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-activated human PBMC cells assessed as inhibition of ATP/nigericin induced IL-1beta secretion prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed