Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50049294
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202784BDBM202784(US9694016, 131 | US9242969, 131 | US10245267, Exam...)
Affinity DataEC50:  20nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202770BDBM202770(US9694016, 117 | US9242969, 117 | US10245267, Exam...)
Affinity DataEC50:  76nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202656BDBM202656(US9694016, 1 | US9242969, 1 | US10245267, Example ...)
Affinity DataEC50:  80nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202798BDBM202798(US9694016, 145 | US9242969, 145 | US10245267, Exam...)
Affinity DataEC50:  80nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202716BDBM202716(US9694016, 62 | US9242969, 62 | US10245267, Exampl...)
Affinity DataEC50:  200nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202772BDBM202772(US9694016, 119 | US9242969, 119 | US10245267, Exam...)
Affinity DataEC50:  200nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237792BDBM50237792(CHEMBL4081025)
Affinity DataEC50:  200nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202780BDBM202780(US9694016, 127 | US9242969, 127 | US10245267, Exam...)
Affinity DataEC50:  250nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202787BDBM202787(US9694016, 134 | US9242969, 134 | US10245267, Exam...)
Affinity DataEC50:  300nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 202791BDBM202791(US9694016, 138 | US9242969, 138 | US10245267, Exam...)
Affinity DataEC50:  460nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237798BDBM50237798(CHEMBL4105276)
Affinity DataEC50:  700nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 77953BDBM77953(US9694016, 390 | US10245267, Example 390 | US10709...)
Affinity DataEC50:  3.96E+3nMAssay Description:Inhibition CRAF in human Calu6 cells assessed as decrease in MEK phosphorylation after 2 hrs by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed