Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 7830
TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221982(US9303035, 6)
Affinity DataIC50: 0.0500nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221986(US9303035, 8.0a)
Affinity DataIC50: 0.0700nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221984(US9303035, 7.0a)
Affinity DataIC50: 0.0900nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221987(US9303035, 8.1a)
Affinity DataIC50: 0.120nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221992(US9303035, 12.2)
Affinity DataIC50: 0.240nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221983(US9303035, 6.1)
Affinity DataIC50: 0.240nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221989(US9303035, 11a)
Affinity DataIC50: 0.310nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221993(US9303035, 12.4)
Affinity DataIC50: 0.540nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221967(US9303035, 2.9)
Affinity DataIC50: 0.590nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221990(US9303035, 12)
Affinity DataIC50: 0.600nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221985(US9303035, 7.1a)
Affinity DataIC50: 0.610nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221994(US9303035, 12.5)
Affinity DataIC50: 0.620nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221970(US9303035, 3.2)
Affinity DataIC50: 0.640nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221969(US9303035, 3.1)
Affinity DataIC50: 0.700nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221952(US9303035, 1.2)
Affinity DataIC50: 1.58nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221958(US9303035, 1.26)
Affinity DataIC50: 1.90nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221996(US9303035, 14)
Affinity DataIC50: 1.96nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221978(US9303035, 4.1 | US9303035, 4.3)
Affinity DataIC50: 3.16nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221981(US9303035, 5.1)
Affinity DataIC50: 3.24nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221995(US9303035, 13)
Affinity DataIC50: 3.53nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221978(US9303035, 4.1 | US9303035, 4.3)
Affinity DataIC50: 4.23nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221934(US9303035, 1.1)
Affinity DataIC50: 4.64nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221941(US9303035, 1.9 | US9303035, 2.4)
Affinity DataIC50: 4.98nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221991(US9303035, 12.1)
Affinity DataIC50: 5.07nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221939(US9303035, 1.7)
Affinity DataIC50: 5.42nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221941(US9303035, 1.9 | US9303035, 2.4)
Affinity DataIC50: 6.31nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221942(US9303035, 1.10)
Affinity DataIC50: 6.37nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221964(US9303035, 2.6)
Affinity DataIC50: 7.62nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221988(US9303035, 9b)
Affinity DataIC50: 8.06nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221974(US9303035, 3.6)
Affinity DataIC50: 8.26nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221944(US9303035, 1.12)
Affinity DataIC50: 10.8nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221946(US9303035, 1.14)
Affinity DataIC50: 11.5nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221949(US9303035, 1.17)
Affinity DataIC50: 18.1nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221955(US9303035, 1.23)
Affinity DataIC50: 29.9nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221935(US9303035, 1.3)
Affinity DataIC50: 30nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetCystic fibrosis transmembrane conductance regulator(Chinese hamster)
Novartis

US Patent
LigandPNGBDBM221979(US9303035, 4.2)
Affinity DataIC50: 30nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent