Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for assayid = 13 entry = 50049298
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238416BDBM50238416(CHEMBL4087470)
Affinity DataIC50: 16nMAssay Description:Inhibition of His-tagged TNKS1 (1091 to 1325 residues) (unknown origin) assessed as reduction in PARsylation of GST-tev-Axin2 preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50238419BDBM50238419(CHEMBL4060134)
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged TNKS1 (1091 to 1325 residues) (unknown origin) assessed as reduction in PARsylation of GST-tev-Axin2 preincubated for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2019
Entry Details Article
PubMed