Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for assayid = 14 entry = 50034221
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50359080(CHEMBL1922660)
Affinity DataIC50: 4nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 3 hr by ELISA in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50052018(MK-591 | Sodium; 3-[3-tert-butylsulfanyl-1-(4-chlo...)
Affinity DataIC50: 12nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 3 hr by ELISA in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297385(3-[3-tert-Butylsulfanyl-1-[4-(6-methoxy-pyridin-3-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 3 hr by ELISA in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 27nMAssay Description:Inhibition of FLAP in human peripheral leukocytes assessed as inhibition of calcium ionophore A23187-induced LTB4 production after 3 hr by ELISA in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)