Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 12239
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM689269(US20240254124, Compound 1 | Synthesis of N-(2-fluo...)
Affinity DataKd: >1.00E+5nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM687756(US20240246972, Compound 3 | Synthesis of N-(1-(3-m...)
Affinity DataKd:  8.90E+4nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Avicenna Biosciences, Inc.

US Patent
LigandPNGBDBM50117930(N-(4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidi...)
Affinity DataKd:  33.3nMAssay Description:Compounds were dissolved in DMSO to a stock concentration of 10 mM and tested in 10-dose IC50 mode, in triplicate, with a 3-fold serial dilution star...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2024
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)