Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50005563
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038269(2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...)
Affinity DataKd:  80nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038267(2-Amino-6,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...)
Affinity DataKd:  500nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  600nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  700nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038272(2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...)
Affinity DataKd:  700nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  1.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038266(2-Amino-8-isopropyl-2,8-dihydro-3H-pyrido[2,3-d]py...)
Affinity DataKd:  1.90E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038264(2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  2.00E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038273(2-Amino-7,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...)
Affinity DataKd:  2.90E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038263(2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  4.00E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038274(2-Amino-6-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  4.60E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038262(2-Amino-5,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...)
Affinity DataKd:  5.10E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038265(2-Amino-8-ethyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimi...)
Affinity DataKd:  1.30E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038271(2-Amino-8-ethyl-6-methyl-2,8-dihydro-3H-pyrido[2,3...)
Affinity DataKd:  1.60E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038260(2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...)
Affinity DataKd:  1.80E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
University of Sydney

Curated by ChEMBL
LigandPNGBDBM50038275(2-Amino-8-methyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  2.10E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed