Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50020493
LigandChemical structure of BindingDB Monomer ID 50630495BDBM50630495(CHEMBL5409389)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-induced human THP-1 cells expressing GFP-tagged ASC assessed as disruption of ASC speck formation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50155926BDBM50155926(CHEMBL3183703)
Affinity DataIC50: 28nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-induced human THP-1 cells expressing GFP-tagged ASC assessed as disruption of ASC speck formation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50553944BDBM50553944(CHEMBL4780624)
Affinity DataIC50: 33nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-induced human THP-1 cells expressing GFP-tagged ASC assessed as disruption of ASC speck formation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed