Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50045691
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075452BDBM50075452(CHEMBL3415315)
Affinity DataIC50: 14nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075454BDBM50075454(CHEMBL3415330)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075455BDBM50075455(CHEMBL3415331)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075458BDBM50075458(CHEMBL3415334)
Affinity DataIC50: 29nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075457BDBM50075457(CHEMBL3415333)
Affinity DataIC50: 49nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075467BDBM50075467(CHEMBL3415342)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075467BDBM50075467(CHEMBL3415342)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075466BDBM50075466(CHEMBL3415341)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075451BDBM50075451(CHEMBL3415314)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075465BDBM50075465(CHEMBL3415340)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075456BDBM50075456(CHEMBL3415332)
Affinity DataIC50: 81nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087267BDBM50087267((S)-4-(2-(N-methylisoquinoline-5-sulfonamido)-3-ox...)
Affinity DataIC50: 143nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50087267BDBM50087267((S)-4-(2-(N-methylisoquinoline-5-sulfonamido)-3-ox...)
Affinity DataIC50: 143nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075462BDBM50075462(CHEMBL3415338)
Affinity DataIC50: 192nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075468BDBM50075468(CHEMBL3415343)
Affinity DataIC50: 253nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075461BDBM50075461(CHEMBL3415337)
Affinity DataIC50: 313nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Human)
Gwangju Institute of Science and Technology (Gist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075467BDBM50075467(CHEMBL3415342)
Affinity DataIC50: 9.80E+4nMAssay Description:Antagonist activity at P2X7 receptor in LPS/IFN-gamma-differentiated human THP1 cells assessed as inhibition of BzATP-induced IL-1beta release preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2016
Entry Details Article
PubMed