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Found 39 of ph data with Target = '3-oxoacyl-[acyl-carrier-protein] synthase 3'
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes)
Quorex Pharmaceuticals

LigandPNGBDBM23585((3-Phenoxybenzoylamino)benzoic acid deriv., 24i | ...)
Affinity DataIC50:  3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23585((3-Phenoxybenzoylamino)benzoic acid deriv., 24i | ...)
Affinity DataIC50:  28nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes)
Quorex Pharmaceuticals

LigandPNGBDBM23586((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Affinity DataIC50:  34nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes)
Quorex Pharmaceuticals

LigandPNGBDBM23584((3-Phenoxybenzoylamino)benzoic acid deriv., 24c | ...)
Affinity DataIC50:  50nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23584((3-Phenoxybenzoylamino)benzoic acid deriv., 24c | ...)
Affinity DataIC50:  56nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23586((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Affinity DataIC50:  62nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23581((3-Phenoxybenzoylamino)benzoic acid deriv., 23b | ...)
Affinity DataIC50:  1.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis)
Portland State University

LigandPNGBDBM68278(Decyl-CoA disulfide 5)
Affinity DataIC50:  1.20E+3nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23570(2-{[4-bromo-3-(diethylsulfamoyl)benzene]amido}benz...)
Affinity DataIC50:  1.60E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23572(2-{[3-(diethylsulfamoyl)-4-phenylbenzene]amido}ben...)
Affinity DataIC50:  1.60E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23578(2-{[4-(cyclopentylmethoxy)-3-(diethylsulfamoyl)ben...)
Affinity DataIC50:  2.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23576(2-{[3-(diethylsulfamoyl)-4-(piperidin-1-yl)benzene...)
Affinity DataIC50:  2.20E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  2.40E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23579((3-Phenoxybenzoylamino)benzoic acid deriv., 15 | 2...)
Affinity DataIC50:  2.70E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  3.80E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23580((3-Phenoxybenzoylamino)benzoic acid deriv., 23a | ...)
Affinity DataIC50:  3.80E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23577(2-{[3-(diethylsulfamoyl)-4-phenoxybenzene]amido}be...)
Affinity DataIC50:  6.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23575(2-{[3-(diethylsulfamoyl)-4-fluorobenzene]amido}ben...)
Affinity DataIC50:  8.40E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus)
Quorex Pharmaceuticals

LigandPNGBDBM23584((3-Phenoxybenzoylamino)benzoic acid deriv., 24c | ...)
Affinity DataIC50:  1.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23574(2-{[3-(diethylsulfamoyl)-4-methoxybenzene]amido}be...)
Affinity DataIC50:  1.14E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus)
Quorex Pharmaceuticals

LigandPNGBDBM23586((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Affinity DataIC50:  1.23E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae)
Quorex Pharmaceuticals

LigandPNGBDBM23586((3-Phenoxybenzoylamino)benzoic acid deriv., 31 | 2...)
Affinity DataIC50:  2.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus)
Quorex Pharmaceuticals

LigandPNGBDBM23585((3-Phenoxybenzoylamino)benzoic acid deriv., 24i | ...)
Affinity DataIC50:  2.40E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23583((3-Phenoxybenzoylamino)benzoic acid deriv., 23d | ...)
Affinity DataIC50:  2.50E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis)
Portland State University

LigandPNGBDBM68277(Octyl-CoA disulfide 4)
Affinity DataIC50:  3.01E+4nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68275(Methyl-CoA disulfide 1)
Affinity DataIC50:  5.71E+4nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae)
Quorex Pharmaceuticals

LigandPNGBDBM23585((3-Phenoxybenzoylamino)benzoic acid deriv., 24i | ...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae)
Quorex Pharmaceuticals

LigandPNGBDBM23584((3-Phenoxybenzoylamino)benzoic acid deriv., 24c | ...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23573(2-{[4-bromo-3-(diethylsulfamoyl)-5-methylbenzene]a...)
Affinity DataIC50:  1.60E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23582((3-Phenoxybenzoylamino)benzoic acid deriv., 23c | ...)
Affinity DataIC50:  1.85E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis)
Portland State University

LigandPNGBDBM68276(Sec-butyl-CoA disulfide 3)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis)
Portland State University

LigandPNGBDBM68274(Butyl-CoA disulfide 2)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis)
Portland State University

LigandPNGBDBM68275(Methyl-CoA disulfide 1)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68278(Decyl-CoA disulfide 5)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68276(Sec-butyl-CoA disulfide 3)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68274(Butyl-CoA disulfide 2)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68277(Octyl-CoA disulfide 4)
Affinity DataIC50: >3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed