Compile Data Set for Download or QSAR
Report error Found 39 of ph data with Target = '3-oxoacyl-[acyl-carrier-protein] synthase 3'
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandPNGBDBM23585(2-{[4-(4-methanesulfonylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandPNGBDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23585(2-{[4-(4-methanesulfonylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 28nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 34nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 56nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 62nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23581(2-[(4-bromo-3-phenoxybenzene)amido]benzoic acid | ...)
Affinity DataIC50: 1.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Portland State University

LigandPNGBDBM68278(Decyl-CoA disulfide 5)
Affinity DataIC50: 1.20E+3nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23570(2-{[4-bromo-3-(diethylsulfamoyl)benzene]amido}benz...)
Affinity DataIC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23572(2-{[3-(diethylsulfamoyl)-4-phenylbenzene]amido}ben...)
Affinity DataIC50: 1.60E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23578(2-{[4-(cyclopentylmethoxy)-3-(diethylsulfamoyl)ben...)
Affinity DataIC50: 2.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23576(2-{[3-(diethylsulfamoyl)-4-(piperidin-1-yl)benzene...)
Affinity DataIC50: 2.20E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandPNGBDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 2.40E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23579(2-[(3-phenoxybenzene)amido]benzoic acid | (3-Pheno...)
Affinity DataIC50: 2.70E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandPNGBDBM23587(2-hydroxy-6-[(3-phenoxy-4-phenylbenzene)amido]benz...)
Affinity DataIC50: 3.80E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23580(2-[(4-fluoro-3-phenoxybenzene)amido]benzoic acid |...)
Affinity DataIC50: 3.80E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23577(2-{[3-(diethylsulfamoyl)-4-phenoxybenzene]amido}be...)
Affinity DataIC50: 6.10E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23575(2-{[3-(diethylsulfamoyl)-4-fluorobenzene]amido}ben...)
Affinity DataIC50: 8.40E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23574(2-{[3-(diethylsulfamoyl)-4-methoxybenzene]amido}be...)
Affinity DataIC50: 1.14E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 1.23E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandPNGBDBM23585(2-{[4-(4-methanesulfonylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 2.40E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23583(2-{[4-(4-methylpiperazin-1-yl)-3-phenoxybenzene]am...)
Affinity DataIC50: 2.50E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Portland State University

LigandPNGBDBM68277(Octyl-CoA disulfide 4)
Affinity DataIC50: 3.01E+4nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68275(Methyl-CoA disulfide 1)
Affinity DataIC50: 5.71E+4nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandPNGBDBM23585(2-{[4-(4-methanesulfonylphenyl)-3-phenoxybenzene]a...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23573(2-{[4-bromo-3-(diethylsulfamoyl)-5-methylbenzene]a...)
Affinity DataIC50: 1.60E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23582(2-{[3-phenoxy-4-(piperazin-1-yl)benzene]amido}benz...)
Affinity DataIC50: 1.85E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68276(Sec-butyl-CoA disulfide 3)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68274(Butyl-CoA disulfide 2)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68278(Decyl-CoA disulfide 5)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Escherichia coli)
Portland State University

LigandPNGBDBM68277(Octyl-CoA disulfide 4)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Portland State University

LigandPNGBDBM68274(Butyl-CoA disulfide 2)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Portland State University

LigandPNGBDBM68275(Methyl-CoA disulfide 1)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Portland State University

LigandPNGBDBM68276(Sec-butyl-CoA disulfide 3)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:Escherichia coli FabH assays were carried out using standard coupled trichloroacetic acid precipitation assay to determine the rate formation of radi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details Article
PubMed