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Report error Found 35 of ph data with Target = '5-hydroxytryptamine receptor 2B'
Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50395587BDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50395569BDBM50395569(CHEMBL2165119 | UNC10099975 | US9156822, 3 or UNC9...)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 50130293BDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  1.40nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 249361BDBM249361(US9464062, 5)
Affinity DataIC50: 41nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 249358BDBM249358(US9464062, 1)
Affinity DataIC50: 126nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 28579BDBM28579(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  130nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 28574BDBM28574(3-amino-N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6...)
Affinity DataKi:  155nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 28580BDBM28580(N-[1-(naphthalene-1-sulfonyl)-1H-indazol-6-yl]pipe...)
Affinity DataKi:  174nM ΔG°:  -38.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/5/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 249360BDBM249360(US9464062, 4)
Affinity DataIC50: 190nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 249359BDBM249359(US9464062, 3)
Affinity DataIC50: 274nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 249363BDBM249363(US9464062, 7)
Affinity DataIC50: 298nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186963BDBM186963(US9079895, 65)
Affinity DataKi:  333nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186962BDBM186962(US9079895, 64)
Affinity DataKi:  441nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 21358BDBM21358(2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...)
Affinity DataKi:  458nM ΔG°:  -35.8kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/7/2008
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186935BDBM186935(US9079895, 23s)
Affinity DataKi:  551nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186923BDBM186923(US9079895, 15r)
Affinity DataKi:  600nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186937BDBM186937(US9079895, 25s)
Affinity DataKi:  658nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186964BDBM186964(US9079895, 66)
Affinity DataKi:  770nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186925BDBM186925(US9079895, 17r)
Affinity DataKi:  788nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186934BDBM186934(US9079895, 22s)
Affinity DataKi:  1.10E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186945BDBM186945(US9079895, 29r)
Affinity DataKi:  1.33E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186927BDBM186927(US9079895, 19s)
Affinity DataKi:  1.45E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186936BDBM186936(US9079895, 24s)
Affinity DataKi:  1.65E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186933BDBM186933(US9079895, 23r)
Affinity DataKi:  1.85E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 249362BDBM249362(US9464062, 6)
Affinity DataIC50: 1.87E+3nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/11/2017
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186932BDBM186932(US9079895, 22r)
Affinity DataKi:  2.36E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186941BDBM186941(US9079895, 27r)
Affinity DataKi:  2.56E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186938BDBM186938(US9079895, 25r)
Affinity DataKi:  2.69E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186939BDBM186939(US9079895, 26r)
Affinity DataKi:  3.17E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186968BDBM186968(US9079895, 70)
Affinity DataKi:  3.46E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186953BDBM186953(US9079895, 60)
Affinity DataKi:  4.61E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186960BDBM186960(US9079895, 62)
Affinity DataKi:  5.18E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186926BDBM186926(US9079895, 18s)
Affinity DataKi:  6.42E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186930BDBM186930(US9079895, 21s | US9079895, 20s)
Affinity DataKi:  7.64E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2B(Mouse)
University of Dundee

US Patent
LigandChemical structure of BindingDB Monomer ID 186928BDBM186928(US9079895, 20r)
Affinity DataKi:  8.81E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.unc....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
US Patent