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Found 22 of ph data with Target = 'Adenosine receptor A3'
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198126((2S,3S,4R,5R)-5-[2-chloro-6-[(3-iodophenyl)methyla...)
Affinity DataKi:  0.220nM ΔG°:  -55.1kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM106372(N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6...)
Affinity DataKi:  72nMpH: 7.4Assay Description:For A1 adenosine receptors, 40 mg of protein were incubated for 60 min at 25°C with [3H]DPCPX 0.5 nM (Kd = 0.4 nM) and increasing concentrations...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM86761(CAS_35920-39-9 | NECA | NSC_448222)
Affinity DataKi:  73nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM106376(N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6...)
Affinity DataKi:  91nMpH: 7.4Assay Description:For A1 adenosine receptors, 40 mg of protein were incubated for 60 min at 25°C with [3H]DPCPX 0.5 nM (Kd = 0.4 nM) and increasing concentrations...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM106373(N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6...)
Affinity DataKi:  190nMpH: 7.4Assay Description:For A1 adenosine receptors, 40 mg of protein were incubated for 60 min at 25°C with [3H]DPCPX 0.5 nM (Kd = 0.4 nM) and increasing concentrations...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM106375(N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6...)
Affinity DataKi:  224nMpH: 7.4Assay Description:For A1 adenosine receptors, 40 mg of protein were incubated for 60 min at 25°C with [3H]DPCPX 0.5 nM (Kd = 0.4 nM) and increasing concentrations...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM106371(N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6...)
Affinity DataKi:  292nMpH: 7.4Assay Description:For A1 adenosine receptors, 40 mg of protein were incubated for 60 min at 25°C with [3H]DPCPX 0.5 nM (Kd = 0.4 nM) and increasing concentrations...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM224619(US9326978, 32)
Affinity DataKi:  410nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM106374(N-[9-(ortho-fluorobenzyl)-2-phenyl-9H-8-azapurin-6...)
Affinity DataKi:  413nMpH: 7.4Assay Description:For A1 adenosine receptors, 40 mg of protein were incubated for 60 min at 25°C with [3H]DPCPX 0.5 nM (Kd = 0.4 nM) and increasing concentrations...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM224617(US9326978, 30)
Affinity DataKi:  786nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM224618(US9326978, 31)
Affinity DataKi:  1.19E+3nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM224621(US9326978, 34)
Affinity DataKi:  1.61E+3nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM224620(US9326978, 33 | US9326978, 49)
Affinity DataKi:  4.69E+3nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM224620(US9326978, 33 | US9326978, 49)
Affinity DataKi:  4.69E+3nMpH: 8.0Assay Description:Each tube in the competitive binding assay contained 100 μl membrane suspension (20 μg protein), 50 μl [125I]-AB-MECA (0.5 nM), and 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198127(4-amino-6-alkyloxy-2-benzylthiopyrimidines (4))
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198128(4-amino-6-alkyloxy-2-benzylthiopyrimidines (5))
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM198129(4-amino-6-alkyloxy-2-benzylthiopyrimidines (6))
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM21173(1,3-dipropyl-8-cyclopentylxanthine | 8-cyclopentyl...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:Aliquots of cell membranes (90 ug) were incubated at 25 °C for 180 min in 500 uL of binding buffer (50 mM Tris-HCl, 5 mM MgCl2, 1 mM EDTA, 2 un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  1.55nMpH: 7.4 T: 2°CAssay Description:.(R)- and (S)-(4-Fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol was tested in a radioligand binding assay, according to th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  28nMpH: 7.4 T: 2°CAssay Description:.(R)- and (S)-(4-Fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol was tested in a radioligand binding assay, according to th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataKd:  28.5nMpH: 7.4 T: 2°CAssay Description:.(R)- and (S)-(4-Fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol was tested in a radioligand binding assay, according to th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit?? Di Napoli Federico Ii

LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataKd:  1.42nMpH: 7.4 T: 2°CAssay Description:.(R)- and (S)-(4-Fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol was tested in a radioligand binding assay, according to th...More data for this Ligand-Target Pair
In DepthDetails US Patent