Compile Data Set for Download or QSAR
Report error Found 55 of ph data with Target = 'Aldo-keto reductase family 1 member C3'
LigandChemical structure of BindingDB Monomer ID 17285BDBM17285((2R,15'S)-5,5,15'-trimethyl-6-oxospiro[oxane-2,14'...)
Affinity DataIC50: 3.20nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 264509BDBM264509(17-(5-fluoropyridin-3-yl)-N-[(R)-2-hydroxypropyl]o...)
Affinity DataIC50: 4nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264475BDBM264475(17-oxooestra-1,3,5(10)-triene-3,11a-diyl diacetate...)
Affinity DataIC50: 4nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264504BDBM264504(N-[(S)-2,3-dihydroxypropyl]-17-(5-fluoropyridin-3-...)
Affinity DataIC50: 4nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264510BDBM264510(N-ethyl-17-(5-fluoropyridin-3-yl)oestra-1,3,5(10),...)
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264493BDBM264493(17-(5-fluoropyridin-3-yl)-N-(1H-tetrazol-5-ylmethy...)
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264492BDBM264492(17-(5-fluoropyridin-3-yl)-N-[2-(1H-tetrazol-5-yl)e...)
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264508BDBM264508(17-(5-fluoropyridin-3-yl)-N-[2-(methylsulphinyl)et...)
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264498BDBM264498(17-(5-fluoropyridin-3-yl)-N-[3-(methylamino)-3-oxo...)
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264497BDBM264497(N-(3-amino-3-oxopropyl)-17-(5-fluoropyridin-3-yl)o...)
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264507BDBM264507(N-[(R)-2,3-dihydroxypropyl]-17-(5-fluoropyridin-3-...)
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264505BDBM264505(17-(5-fluoropyridin-3-yl)-N-(3-hydroxypropyl)-N-me...)
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264472BDBM264472(17-(pyridin-3-yl)oestra-1,3,5(10),16-tetraene-3-ca...)
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264516BDBM264516(17-(5-fluoropyridin-3-yl)-N-[(S)-2-hydroxypropyl]o...)
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264515BDBM264515(17-(5-fluoropyridin-3-yl)-N-[(S)-2-hydroxypropyl]o...)
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 17285BDBM17285((2R,15'S)-5,5,15'-trimethyl-6-oxospiro[oxane-2,14'...)
Affinity DataKi:  6.90nM ΔG°:  -48.5kJ/molepH: 7.5 T: 2°CAssay Description:A radioactive assay was used for the enzyme kinetics in the presence of EM1404 at different concentrations for its Ki determination. Reactions were i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 264513BDBM264513(17-(5-fluoropyridin-3-yl)-N-[(3-methyloxetan-3-yl)...)
Affinity DataIC50: 7nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264511BDBM264511(17-(5-fluoropyridin-3-yl)-N-(2-methoxyethyl)oestra...)
Affinity DataIC50: 8nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264494BDBM264494(17-(3-pyridyl)-N-(2-sulphamoylethyl)oestra-1,3,5(1...)
Affinity DataIC50: 9nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264499BDBM264499(17-(5-fluoropyridin-3-yl)oestra-1,3,5(10),16-tetra...)
Affinity DataIC50: 9nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 17286BDBM17286((2R,15'S)-5'-(2-methoxyethoxy)-5,5,15'-trimethyl-6...)
Affinity DataIC50: 9.5nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 264500BDBM264500(1-{[17-(5-fluoropyridin-3-yl)oestra-1,3,5(10),16-t...)
Affinity DataIC50: 10nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264512BDBM264512(17-(5-fluoropyridin-3-yl)-N-[2-(isopropylsulphonyl...)
Affinity DataIC50: 11nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264503BDBM264503(N-ethyl-17-(5-fluoropyridin-3-yl)-N-(2-hydroxyethy...)
Affinity DataIC50: 11nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264491BDBM264491(17-(5-fluoropyridin-3-yl)-N-[(RS)-3,3,3-trifluoro-...)
Affinity DataIC50: 12nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264501BDBM264501(1-{[17-(5-fluoropyridin-3-yl)oestra-1,3,5(10),16-t...)
Affinity DataIC50: 12nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264514BDBM264514(17-(5-fluoropyridin-3-yl)-N-(2-hydroxyethyl)-N-met...)
Affinity DataIC50: 12nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 17287BDBM17287((2R,15'S)-5'-(2-methoxyethoxy)-5,5,15'-trimethyl-6...)
Affinity DataIC50: 13nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 264487BDBM264487(17-(5-fluoropyridin-3-yl)-N-[(R)-1-(hydroxymethyl)...)
Affinity DataIC50: 15nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264495BDBM264495(N-(2-sulphamoylethyl)-17-[5-(trifluoromethyl)pyrid...)
Affinity DataIC50: 17nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264506BDBM264506(N-[(RS)-2,3-dihydroxypropyl]-17-(5-fluoropyridin-3...)
Affinity DataIC50: 17nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264502BDBM264502(17-(5-fluoropyridin-3-yl)-N-{2-methyl-2-[(methylsu...)
Affinity DataIC50: 19nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264483BDBM264483(17-(5-fluoropyridin-3-yl)-N-[(R)-3-(hydroxymethyl)...)
Affinity DataIC50: 21nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264486BDBM264486(3-cyanooestra-1,3,5(10),16-tetraen-17-yl trifluoro...)
Affinity DataIC50: 25nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264478BDBM264478(11 -fluoro-17-(5-fluoropyridin-3-yl)oestra-1,3,5(1...)
Affinity DataIC50: 27nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264488BDBM264488(17-(5-fluoropyridin-3-yl)oestra-1,3,5(10),16-tetra...)
Affinity DataIC50: 29nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264482BDBM264482(methyl 11 -fluoro-17-(5-fluoropyridin-3-yl)oestra-...)
Affinity DataIC50: 34nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264489BDBM264489(rel-17-(5-fluoropyridin-3-yl)-N-[(1R,2R)-2-hydroxy...)
Affinity DataIC50: 45nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264474BDBM264474(17-[5-(trifluoromethyl)pyridin-3-yl]oestra-1,3,5(1...)
Affinity DataIC50: 46nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264496BDBM264496(N-[2-(N-methylsulphamoyl)ethyl]-17-[5-(trifluorome...)
Affinity DataIC50: 48nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264485BDBM264485(17-iodooestra-1,3,5(10),16-tetraene-3-carboxamide ...)
Affinity DataIC50: 54nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264490BDBM264490(17-(5-fluoropyridin-3-yl)-N-(2-hydroxyethyl)-N-iso...)
Affinity DataIC50: 60nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264480BDBM264480(methyl 11a-acetoxy-17-(5-fluoropyridin-3-yl)oestra...)
Affinity DataIC50: 61nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264479BDBM264479(11 -fluoro-17-(5-fluoropyridin-3-yl)-N-(2-sulphamo...)
Affinity DataIC50: 73nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264481BDBM264481(methyl 17-(5-fluoropyridin-3-yl)-11a-hydroxyoestra...)
Affinity DataIC50: 97nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264484BDBM264484(17-(5-fluoropyridin-3-yl)-N-[1-(hydroxymethyl)cycl...)
Affinity DataIC50: 108nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 264517BDBM264517(17-(pyrimidin-5-yl)-N-(2-sulphamoylethyl)oestra-1,...)
Affinity DataIC50: 119nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 17636BDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataKi:  140nM ΔG°:  -39.8kJ/molepH: 7.0 T: 2°CAssay Description:A fluorescence assay was used to determine the kinetic constants for the oxidation of 3alpha-androstanediol. The fluorescence emission of NADPH at 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 264473BDBM264473(17-(5-methoxypyridin-3-yl)oestra-1,3,5(10),16-tetr...)
Affinity DataIC50: 189nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2018
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataKi:  270nM ΔG°:  -38.1kJ/molepH: 7.0 T: 2°CAssay Description:A fluorescence assay was used to determine the kinetic constants for the oxidation of 3alpha-androstanediol. The fluorescence emission of NADPH at 45...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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