Compile Data Set for Download or QSAR
Report error Found 1092 of ph data with Target = 'Amine oxidase [flavin-containing] A'
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 218829BDBM218829(1,4-Bis(2-pentanoylimino-5-(2-methoxy-2-oxoethylid...)
Affinity DataIC50: 1nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11006BDBM11006(5-(furan-2-yl)-3-(4-methylphenyl)-4,5-dihydro-1H-p...)
Affinity DataKi:  4nM ΔG°:  -50.0kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 15581BDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 4.5nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 15581BDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 4.5nMpH: 7.4 T: 2°CAssay Description:The effects of the test compounds on hMAO isoform enzymatic activity were evaluated by measuring their effects on the production of hydrogen peroxide...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11016BDBM11016((5S)-5-(4-chlorophenyl)-3-(4-fluorophenyl)-4,5-dih...)
Affinity DataKi:  5nM ΔG°:  -49.4kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11005BDBM11005(3,5-bis(4-methylphenyl)-4,5-dihydro-1H-pyrazole-1-...)
Affinity DataKi:  6nM ΔG°:  -49.0kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11007BDBM11007(5-(4-chlorophenyl)-3-(4-fluorophenyl)-4,5-dihydro-...)
Affinity DataKi:  6nM ΔG°:  -49.0kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11008BDBM11008(3-(4-fluorophenyl)-5-(4-methylphenyl)-4,5-dihydro-...)
Affinity DataKi:  7nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15586BDBM15586(N-methyl-N-(2-phenylethyl)-1H-pyrrole-2-carboxamid...)
Affinity DataKi:  7nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
The Weizmann Institute of Science

LigandChemical structure of BindingDB Monomer ID 36552BDBM36552(Prochelators, 2)
Affinity DataIC50: 7.70nMpH: 7.4 T: 2°CAssay Description:Inhibition of MAO activity in rat brain homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 15581BDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataIC50: 7.90nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11009BDBM11009(3-(4-fluorophenyl)-5-(furan-2-yl)-4,5-dihydro-1H-p...)
Affinity DataKi:  8nM ΔG°:  -48.2kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 218826BDBM218826(1,2-Bis(2-(2-chlorobenzoylimino)-5-(2-methoxy-2-ox...)
Affinity DataIC50: 9nMpH: 7.4Assay Description:The assay was performed in a polystyrene 96-well plate having flat bottom containing 200 μL of the total reaction mixture. For each assay, mixtu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
The Weizmann Institute of Science

LigandChemical structure of BindingDB Monomer ID 36553BDBM36553(Prochelators, 3)
Affinity DataIC50: 9.60nMpH: 7.4 T: 2°CAssay Description:Inhibition of MAO activity in rat brain homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/1/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 15613BDBM15613(MCL | Aurorix | 4-chloro-N-[2-(morpholin-4-yl)ethy...)
Affinity DataKi:  10nMpH: 7.4Assay Description:Study medium contained 0.1 mL of sodium phosphate buffer (0.05 M, pH 7.4), various concentrations of the newly synthesized compounds or reference com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11017BDBM11017((5R)-5-(4-chlorophenyl)-3-(4-fluorophenyl)-4,5-dih...)
Affinity DataKi:  12nM ΔG°:  -47.2kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11015BDBM11015((5R)-5-(4-chlorophenyl)-3-(4-methylphenyl)-4,5-dih...)
Affinity DataKi:  13nM ΔG°:  -47.0kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15595BDBM15595((2-phenylethyl)(1H-pyrrol-2-ylmethyl)amine | N-(2-...)
Affinity DataKi:  20nM ΔG°:  -45.9kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15593BDBM15593(benzyl[(1-methyl-1H-pyrrol-2-yl)methyl]amine | N-(...)
Affinity DataKi:  24nM ΔG°:  -45.4kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11013BDBM11013(3,5-bis(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-c...)
Affinity DataKi:  27nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11004BDBM11004(5-(4-chlorophenyl)-3-(4-methylphenyl)-4,5-dihydro-...)
Affinity DataKi:  31nM ΔG°:  -44.7kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15588BDBM15588(N-(3-Phenylpropyl),N-methyl-1H-pyrrole-2-carboxami...)
Affinity DataKi:  40nM ΔG°:  -44.1kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11010BDBM11010(5-(4-chlorophenyl)-3-(thiophen-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  41nM ΔG°:  -44.0kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
The Weizmann Institute of Science

LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:A fluorimetric method reported by Matsumoto et al.[T. Matsumoto, O. Suzuki, T. Furuta, M. Asai, Y. Kurokawa, Y. Nimura, Y. Katsumata, I. Takahashi. C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15596BDBM15596(methyl(2-phenylethyl)(1H-pyrrol-2-ylmethyl)amine |...)
Affinity DataKi:  50nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15597BDBM15597(N-Methyl,N-(3-phenylpropyl),N-(pyrrol-2-ylmethyl)a...)
Affinity DataKi:  50nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11011BDBM11011(5-(4-methylphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1...)
Affinity DataKi:  50nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 179976BDBM179976(US9676701, 116 3-(5-((trans)-2-aminocyclopropyl)th...)
Affinity DataKi:  50nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11012BDBM11012(5-(furan-2-yl)-3-(thiophen-2-yl)-4,5-dihydro-1H-py...)
Affinity DataKi:  50nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 11014BDBM11014((-)-(S)1 | (5S)-5-(4-chlorophenyl)-3-(4-methylphen...)
Affinity DataKi:  50nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kynuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2006
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15581BDBM15581(US8633208, Clorgyline | [3-(2,4-dichlorophenoxy)pr...)
Affinity DataKi:  54nM ΔG°:  -43.3kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15589BDBM15589(N-(4-Phenylbutyl)-1H-pyrrole-2-carboxamide | pyrro...)
Affinity DataKi:  55nM ΔG°:  -43.2kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 195556BDBM195556((2E)-2-(Pyridin-3-ylmethylidene)-2,3-dihydro-1H-in...)
Affinity DataIC50: 61nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15590BDBM15590(N-methyl-N-(4-phenylbutyl)-1H-pyrrole-2-carboxamid...)
Affinity DataKi:  90nM ΔG°:  -42.0kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15598BDBM15598(methyl(4-phenylbutyl)(1H-pyrrol-2-ylmethyl)amine |...)
Affinity DataKi:  100nM ΔG°:  -41.7kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15594BDBM15594(N-Methyl,N-(benzy),N-(1-methylpyrrol-2-ylmethyl)am...)
Affinity DataKi:  150nM ΔG°:  -40.6kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 195569BDBM195569((2E)-2-[(5-Bromofuran-2-yl)methylidene]-5-methoxy-...)
Affinity DataIC50: 183nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15583BDBM15583(CHEMBL174040 | N-Benzyl-1H-pyrrole-2-carboxamide |...)
Affinity DataKi:  250nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 195559BDBM195559((2E)-5-Methoxy-2-(pyridin-2-ylmethylidene)-2,3-dih...)
Affinity DataIC50: 302nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 195564BDBM195564((2E)-2-(Thiophen-3-ylmethylidene)-2,3-dihydro-1H-i...)
Affinity DataIC50: 322nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15591BDBM15591(N-(Benzyl),N-(pyrrol-2-ylmethyl)amine | benzyl(1H-...)
Affinity DataKi:  350nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 86776BDBM86776(Phthalonitrile analogue, 4e)
Affinity DataIC50: 399nMpH: 7.4 T: 2°CAssay Description:MAO inhibition potencies of phthalonitrile, benzonitrile and benzyl phenyl ether analogs, recombinant human MAO-A and -B were employed as enzyme sour...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2012
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15582BDBM15582(N-Phenyl-1H-pyrrole-2-carboxamide | pyrrole inhibi...)
Affinity DataKi:  400nM ΔG°:  -38.1kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Bovine)
Sapienza University of Rome

LigandChemical structure of BindingDB Monomer ID 15585BDBM15585(N-2-Phenylethyl-1H-pyrrole-2-carboxamide | N-(2-ph...)
Affinity DataKi:  420nM ΔG°:  -38.0kJ/molepH: 7.4 T: 2°CAssay Description:MAO A and MAO B activities were determined spectrophotometrically using kinuramine as substrates. Fluorimetric measurements were recorded with a Perk...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 195560BDBM195560((2E)-2-[(2-Chloropyridin-3-yl)methylidene]-2,3-dih...)
Affinity DataIC50: 471nMpH: 7.4Assay Description:Recombinant human MAO-A and MAO-B were used for these studies and kynuramine served as enzyme substrate. Kynuramine is oxidised by both MAO isoforms ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2016
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 92654BDBM92654(C7-substituted chromone derivative, 3e)
Affinity DataIC50: 495nMpH: 7.4 T: 2°CAssay Description:Inhibition studies using recombinant human MAO-A and MAO-B that were obtained from commercial sources (Sigma-Aldrich).More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 50346586BDBM50346586(CHEMBL1795981 | US8765820, 5a)
Affinity DataKi:  500nMpH: 7.5Assay Description:Human recombinant MAO A and MAO B were expressed in Pichia pastoris and purified as published (Binda C, et al., Proc. Natl. Acad. Sci. USA 100: 9750-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 179853BDBM179853(US9676701, 87 4′-((trans)-2-aminocyclopropyl...)
Affinity DataKi:  550nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 179944BDBM179944(US9676701, 106 4′-((trans)-2-aminocyclopropy...)
Affinity DataKi:  550nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

TargetAmine oxidase [flavin-containing] A(Human)
Quaid-I-Azam University

LigandChemical structure of BindingDB Monomer ID 179860BDBM179860(US9676701, 94 N-(4′-((trans)-2-aminocyclopro...)
Affinity DataKi:  550nMpH: 7.5Assay Description:Assays were conducted in 96-well black plates with clear bottom (Corning) in a final volume of 100 μL. The assay buffer was 100 mM HEPES, pH 7.5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/16/2018
Entry Details
US Patent

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