Report error Found 138 of ph data with Target = 'Aurora kinase B'
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: <1nM ΔG°: <-50.9kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 2nM ΔG°: -49.2kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataIC50: 5.93nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataIC50: 6.73nMpH: 7.4Assay Description:To determine Aurora B activity of representative compounds of the invention, Active Aurora B enzyme (recombinant residues 1-344) and INCENP (recombin...More data for this Ligand-Target Pair
Affinity DataIC50: 7.87nMpH: 7.4Assay Description:To determine Aurora B activity of representative compounds of the invention, Active Aurora B enzyme (recombinant residues 1-344) and INCENP (recombin...More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -45.7kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataIC50: 8.44nMpH: 7.4Assay Description:To determine Aurora B activity of representative compounds of the invention, Active Aurora B enzyme (recombinant residues 1-344) and INCENP (recombin...More data for this Ligand-Target Pair
Affinity DataIC50: 8.78nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataKi: 9nM ΔG°: -45.5kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Affinity DataIC50: 9.36nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
Affinity DataIC50: 11.2nMpH: 7.4Assay Description:To determine Aurora B activity of representative compounds of the invention, Active Aurora B enzyme (recombinant residues 1-344) and INCENP (recombin...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataKi: 13nM ΔG°: -44.6kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataIC50: 13.9nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataKi: 14nM ΔG°: -44.4kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataIC50: 14.2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataIC50: 14.8nMpH: 7.4Assay Description:To determine Aurora B activity of representative compounds of the invention, Active Aurora B enzyme (recombinant residues 1-344) and INCENP (recombin...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
Affinity DataIC50: 15.2nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed at Reaction Biology Corp., Malvern, Pa., USA, using the following general procedure:1) Prepare indicated substrate in fr...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 8.5 T: 2°CAssay Description:Assays for Aurora kinase was performed in a DELFIA format. Aurora enzyme was incubated with test compound and cross-tide substrate in the reaction bu...More data for this Ligand-Target Pair
Affinity DataKi: 18nM ΔG°: -43.8kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
