Compile Data Set for Download or QSAR
Report error Found 3724 of ph data with Target = 'Beta-secretase 1'
TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 16254BDBM16254(N2-[(2R,4S,5S)-5-{[N-{[(2,5-dimethyl-1,3-oxazol-4-...)
Affinity DataKi:  0.120nM ΔG°:  -58.9kJ/molepH: 4.5 T: 2°CAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 147165BDBM147165(US8957083, 39)
Affinity DataIC50: 0.200nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 149348BDBM149348(US8962859, 8B)
Affinity DataIC50: 0.300nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 16253BDBM16253((3,5-dimethyl-1H-pyrazol-1-yl)methyl N-[(1R)-1-{[(...)
Affinity DataKi:  0.300nM ΔG°:  -56.5kJ/molepH: 4.5 T: 2°CAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 147160BDBM147160(US8957083, 34)
Affinity DataIC50: 0.300nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150692BDBM150692(US8987254, 7)
Affinity DataIC50: 0.358nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 149352BDBM149352(US8962859, 15)
Affinity DataIC50: 0.400nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 149350BDBM149350(US8962859, 13)
Affinity DataIC50: 0.400nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220775BDBM220775(US9296759, 48)
Affinity DataIC50: 0.400nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220852BDBM220852(US9296759, 115)
Affinity DataIC50: 0.400nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150690BDBM150690(US8987254, 5)
Affinity DataIC50: 0.450nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150687BDBM150687(US8987254, 2)
Affinity DataIC50: 0.482nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258901BDBM258901(US9499502, 9b)
Affinity DataKi: <0.5nM ΔG°: <-54.0kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258899BDBM258899(US9499502, 9)
Affinity DataKi: <0.5nM ΔG°: <-54.0kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 50393096BDBM50393096(CHEMBL2152911 | US9346827, 15)
Affinity DataIC50: 0.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 147154BDBM147154(US8957083, 32 | US8957083, 30)
Affinity DataIC50: 0.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 50393095BDBM50393095(CHEMBL2152910 | US9346827, 14)
Affinity DataIC50: 0.5nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 242250BDBM242250(US9416129, 28)
Affinity DataKi:  0.5nM ΔG°:  -54.0kJ/molepH: 5.0 T: 2°CAssay Description:Varying concentrations of inhibitors at 3× the final desired concentration in a volume of 10 μl are preincubated with purified human BACE1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150688BDBM150688(US8987254, 3 | US9999624, 3)
Affinity DataIC50: 0.554nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150689BDBM150689(US8987254, 4)
Affinity DataIC50: 0.569nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 136733BDBM136733(US8865911, 20a Isomer 1)
Affinity DataIC50: 0.570nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258909BDBM258909(US9499502, 9j)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 149353BDBM149353(US8962859, 9B | BDBM149355)
Affinity DataIC50: 0.600nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258902BDBM258902(US9499502, 9c)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 147184BDBM147184(US8957083, 26)
Affinity DataIC50: 0.600nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220822BDBM220822(US9296759, 88)
Affinity DataIC50: 0.600nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258897BDBM258897(US9499502, 7)
Affinity DataKi:  0.600nM ΔG°:  -53.5kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220801BDBM220801(US9296759, 69)
Affinity DataIC50: 0.600nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220803BDBM220803(US9296759, 71)
Affinity DataIC50: 0.600nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220835BDBM220835(US9296759, 100)
Affinity DataIC50: 0.600nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150686BDBM150686(US8987254, 1 | US9999624, 1)
Affinity DataIC50: 0.610nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 136738BDBM136738(US8865911, 20d Isomer 1)
Affinity DataIC50: 0.630nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258893BDBM258893(US9499502, 3)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 136799BDBM136799(US8865911, 48 Isomer 6 | US8865911, 48 Isomer 5 | ...)
Affinity DataIC50: 0.700nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 149353BDBM149353(US8962859, 9B | BDBM149355)
Affinity DataIC50: 0.700nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 214839BDBM214839(US9296734, 39)
Affinity DataIC50: 0.700nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 136858BDBM136858(US8865911, 94 Isomer 2 | US8865911, 94 Isomer 1 | ...)
Affinity DataIC50: 0.700nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258904BDBM258904(US9499502, 9e)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 147185BDBM147185(US8957083, 27)
Affinity DataIC50: 0.700nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 149356BDBM149356(US8962859, 17)
Affinity DataIC50: 0.700nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 258896BDBM258896(US9499502, 6)
Affinity DataKi:  0.700nM ΔG°:  -53.1kJ/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 136863BDBM136863(US8865911, 100 | US10231967, Example 100 | US99189...)
Affinity DataIC50: 0.720nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150693BDBM150693(US8987254, 8 | US9999624, 9)
Affinity DataIC50: 0.730nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 150691BDBM150691(US8987254, 6 | US9999624, 7)
Affinity DataIC50: 0.739nMpH: 4.6 T: 2°CAssay Description:Serial dilutions of test compounds are prepared as described above. Compounds are further diluted 20x in KH2PO4 buffer. Ten uL of each dilution is ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220796BDBM220796(US9296759, 64)
Affinity DataIC50: 0.740nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220800BDBM220800(US9296759, 68)
Affinity DataIC50: 0.800nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 220834BDBM220834(US9296759, 99)
Affinity DataIC50: 0.800nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 136855BDBM136855(US8865911, 289 | US8865911, 92 Isomer 1 | US102319...)
Affinity DataIC50: 0.840nMpH: 9.2Assay Description:TR-FRET AssayThe beta-secretase enzyme used in the TR-FRET is prepared as follows: The cDNA for the soluble part of the human beta-Secretase (AA 1-AA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 242270BDBM242270(US9416129, 48)
Affinity DataKi:  0.870nM ΔG°:  -52.6kJ/molepH: 5.0 T: 2°CAssay Description:Varying concentrations of inhibitors at 3× the final desired concentration in a volume of 10 μl are preincubated with purified human BACE1 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Purdue University

LigandChemical structure of BindingDB Monomer ID 214961BDBM214961(US9296734, 155)
Affinity DataIC50: 0.870nMpH: 4.2Assay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2017
Entry Details
US Patent

Displayed 1 to 50 (of 3724 total ) | Next | Last >>
Jump to: