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Report error Found 34 of ph data with Target = 'Calcitonin gene-related peptide type 1 receptor'
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173468BDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50: 0.0300nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103495BDBM103495(US8552023, 7)
Affinity DataKi:  0.0410nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103499BDBM103499(US8552023, 11)
Affinity DataKi:  0.0500nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173482BDBM50173482(4-(2-Oxo-4-phenyl-2,3-dihydro-imidazol-1-yl)-piper...)
Affinity DataIC50: 0.0500nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173468BDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50: 0.0600nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]CGRP as radioligand after 180 minutes of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103494BDBM103494(US8552023, 6)
Affinity DataKi:  0.0650nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103501BDBM103501(US8552023, 13)
Affinity DataKi:  0.130nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173475BDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 0.200nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441044BDBM50441044(CHEMBL2430166 | US9695176, 4)
Affinity DataIC50: 0.220nMpH: 7.5 T: 2°CAssay Description:The compounds of invention were solubilized and carried through serial dilutions using 100% DMSO. Aliquots from the compound serial dilutions were fu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441043BDBM50441043(CHEMBL2430165 | US9695176, 1)
Affinity DataIC50: 0.260nMpH: 7.5 T: 2°CAssay Description:The compounds of invention were solubilized and carried through serial dilutions using 100% DMSO. Aliquots from the compound serial dilutions were fu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 103496BDBM103496(US8552023, 8)
Affinity DataKi:  0.430nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441042BDBM50441042(CHEMBL2430164 | US9695176, 2)
Affinity DataIC50: 1.70nMpH: 7.5 T: 2°CAssay Description:The compounds of invention were solubilized and carried through serial dilutions using 100% DMSO. Aliquots from the compound serial dilutions were fu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173475BDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 2.70nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in marmoset tissue homogenates using [125I]CGRP as radioligand after 180 minutes of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50441041BDBM50441041(CHEMBL2430163 | US9695176, 3)
Affinity DataIC50: 2.95nMpH: 7.5 T: 2°CAssay Description:The compounds of invention were solubilized and carried through serial dilutions using 100% DMSO. Aliquots from the compound serial dilutions were fu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2018
Entry Details
US Patent

TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173472BDBM50173472(4-(1-Phenyl-ureido)-piperidine-1-carboxylic acid [...)
Affinity DataIC50: 4.70nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173468BDBM50173468(4-(2-Oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin...)
Affinity DataIC50: 6.40nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]CGRP as radioligand after 180 minutes of incubation at pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173486BDBM50173486(4-(2-Oxo-benzooxazol-3-yl)-piperidine-1-carboxylic...)
Affinity DataIC50: 44nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173475BDBM50173475(4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin...)
Affinity DataIC50: 56.7nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]CGRP as radioligand after 180 minutes of incubation at pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173477BDBM50173477((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50: 200nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173473BDBM50173473(4-(2-Methoxy-phenyl)-piperazine-1-carboxylic acid ...)
Affinity DataIC50: 226nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173478BDBM50173478(4-(2-Methoxy-phenyl)-piperidine-1-carboxylic acid ...)
Affinity DataIC50: 250nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173476BDBM50173476((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50: 1.00E+3nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173471BDBM50173471(N-{(S)-2-(4-Amino-3,5-dibromo-phenyl)-1-[(R)-5-ami...)
Affinity DataIC50: 1.03E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173467BDBM50173467((R)-6-Amino-2-((S)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 1.30E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173479BDBM50173479((R)-6-Amino-2-[(S)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 1.70E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173485BDBM50173485((R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-...)
Affinity DataIC50: 4.00E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173484BDBM50173484((R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-...)
Affinity DataIC50: 5.00E+4nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Rat)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173477BDBM50173477((S)-N-[(R)-5-Amino-1-(4-pyridin-4-yl-piperazine-1-...)
Affinity DataIC50: 7.05E+4nMpH: 7.4Assay Description:Affinity against calcitonin gene related peptide receptor (1 uM) in rat spleen using [125I]CGRP as radioligand after 180 minutes of incubation at pH ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173481BDBM50173481((R)-6-Amino-2-[(S)-3-(4-amino-3,5-dibromo-phenyl)-...)
Affinity DataIC50: 1.96E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173483BDBM50173483((S)-6-Amino-2-[(R)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173474BDBM50173474(N-{(S)-2-(4-Amino-3,5-dibromo-phenyl)-1-[(R)-5-ami...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173470BDBM50173470((R)-6-Amino-2-[(R)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173469BDBM50173469((S)-6-Amino-2-[(S)-3-(3,5-dibromo-4-hydroxy-phenyl...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50173480BDBM50173480(N-{(S)-2-(4-Amino-3,5-dibromo-phenyl)-1-[(R)-5-ami...)
Affinity DataIC50: 3.00E+5nMpH: 7.4Assay Description:Affinity against human calcitonin gene related peptide receptor (1 uM) expressed in SK-N-MC cells using [125I]-CGRP as radioligand after 180 minutes ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed